100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Combined Immunology HMX; Questions & Answers 100% Correct $26.49   Add to cart

Exam (elaborations)

Combined Immunology HMX; Questions & Answers 100% Correct

 7 views  0 purchase
  • Course
  • HMX
  • Institution
  • HMX

Combined Immunology HMX; Questions & Answers 100% Correct ______________________ is the transfer of tissue/organ from one individual to another Answer-Transplantation _________________________ is the transfer of blood cells/blood products from one individual to another Answer-Transfusion ...

[Show more]

Preview 4 out of 195  pages

  • August 8, 2024
  • 195
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • HMX
  • HMX
avatar-seller
GOLDTUTORS
Combined Immunology HMX; Questions &
Answers 100% Correct
______________________ is the transfer of tissue/organ from one individual to another
Answer-Transplantation




_________________________ is the transfer of blood cells/blood products from one individual
to another Answer-Transfusion




_________________ transplant is the most common transplantation Answer-kidney




_____________________ transfusion is the most common transfusion Answer-red blood
cell



Individuals who are not identical twins differ in many genes that they do not inherit. This means
individuals will have different proteins based on these different genes. These differences are
called ______________________ Answer-polymorphisms




In transplantation, if one person is a donor and another is a recipient, then there might be a
difference in proteins between each person. So, when an organ is transplanted, the recipient's
immune system can detect the transplanted cells as non-self and lead an attack against them.
This attack involves ________________ and ____ cells and is called an ___________________
________________ _______________ Answer-antibodies

T cells



allogeneic immune response

, Combined Immunology HMX; Questions &
Answers 100% Correct
The recipient's T cells and antibodies that enter the implanted organ after transplantation cause
inflammation in the organ as if the organ is a foreign invader, like a microbe. This leads to
injury/death of the implanted organ. This is called _________________ _______________
Answer-transplant rejection




The most polymorphic genes in our entire genome are the _____________________
___________________ _________________ genes. Answer-major histocompatibility
complex (aka HLA genes)




MHC class II has the variants: __________, __________, and _________ proteins
Answer-DP

DQ

DR




MHC class I has the variants: ____________, ______________ and _________ Answer-A

B

C




If we take all the different alleles in the human population that encode normal functioning
versions of the MHC class I and II variants, there are over ______________ alleles
Answer-5,000

, Combined Immunology HMX; Questions &
Answers 100% Correct
HLA-B has over _______________ alleles Answer-2,500




_______ is the major immunological barrier to transplantation Answer-MHC




______________ have carbohydrates on their surface, but they differ from one person to
another Answer-RBCs




The antigens on red blood cells include: _______, _________, _________ or _________
Answer-A

B

AB

O




If someone is type A, this means they have the A antigen and they have antibodies that
recognize the antigens that they do not express. So, type A has natural ______ antibodies that
recognize the ______ antigen. Type B has antibodies that recognize the ______ antigen. Type O
has antibodies that recognize the ________ and _______ antigen. Type AB has _________
antibodies Answer-IgM




B



A

, Combined Immunology HMX; Questions &
Answers 100% Correct
A

B



neither




If you want to transfuse blood across individuals, then the antibodies can cause trouble. For
example, if type A is transfused into someone with type B, then the recipient with type B (who
has antibodies against type A) will cause the destruction of type A blood either by
___________________ activation or _________________. This is called a
____________________ ________________ Answer-complement

phagocytosis




transfusion reaction



Given what you have learned about the genetic loci that are most important for transplant
compatibility, it is likely that ____________ are the primary mediators of transplant rejection.




1. B lymphocytes

2. T lymphocytes

3. macrophages

4. neutrophils Answer-2. T lymphocytes

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller GOLDTUTORS. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $26.49. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

80461 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$26.49
  • (0)
  Add to cart