Nursing Considerations of Cephalosporins - Answer - take with food
- avoid alcohol
- cross allergy with PCN (don't take if allergic to PCN)
Carbapenems - Answer Meropenem
Indications of Carbapenems - Answer Treatment of serious infections caused by
susceptible bacteria
Action of Carbapenems - Answer Inhibit cell membrane synthesis in susceptible
bacteria, leading to cell death
Contraindications/Cautions of Carbapenems - Answer Known allergy to any of the
carbapenems or betalactams, seizure disorders, meningitis, pregnancy and lactation
Adverse effects of Carbapenems - Answer Pseudomembranous colitis, C. diff diarrhea,
and nausea and vomiting can lead to serious dehydration and electrolyte imbalances, as
well as to new serious infections/superinfections
Nursing Considerations of Carbapenems - Answer Observe intravenous site closely for
extravasation. Observe for signs of renal, hepatic, or hematological dysfunction.
Observe for skin rashes. Measure urine output.
Indications of Vancomycin - Answer Treatment of serious infections caused by bacteria,
especially MRSA
Action of Vancomycin - Answer Binds to bacterial cell wall, resulting in cell death
Contraindications/Cautions of Vancomycin - Answer May affect the kidneys (BUN)
Adverse effects of Vancomycin - Answer nephrotoxicity, ototoxicity, red man syndrome
Nursing Considerations of Vancomycin - Answer - Monitor blood levels to ensure
therapeutic levels and prevent toxicity
- Ensure adequate hydration (2L of fluids/24hrs) to prevent nephrotoxicity
- Infuse over 60 minutes
- Monitor drug levels
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