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Clinical Immunology test questions fully solved & updated
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Clinical Immunology test questions fully solved & updated
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Clinical Immunology testquestions fully solved &
updated
what is the difference between immunology and immunity? - answer
ology= study; host defense mechanisms
-unity: ability of the host to protect itself against foreign organisms
What is the difference between innate and acquired immunity (big
picture)? - answer innate: 1st line defense, nonspecific (physical
barriers, PMNs, complement system NK cells
Acquired: requires antigenic stimulation
B-cells (humoral)
T- cells (cellular)
What are some major components of the complement cascade and
what are they comprised of? - answer comprised of serum proteins
that amplify the innate immune response and connect with the
adaptive immune system;
-important defense against pyogenic (bacterial) infection
-deficiencies lead to overwhelming infection and sepsis.
, What are the 3 pathways of the innate immune system - answer
Classical (antibody-antigen complex)
lectin (serum lectin binds to mannose residues on pathogens)
alternative (pathogen cell membranes)
What are the two components of acquired immunity? (big picture) -
answer Lymphocytes (BTNK)
immunoglobulins (antibodies)
What are 2 professional Antigen presenting cells? - answer
macrophages, B- cells
What are 4 atypical Antigen presenting cells? - answer Mast cells,
basophil, eosinophil, ILC3s
What is the main cell type of cellular immunity and what does it assist
in? (big picture) - answer T-cells--> (originate in the thymus)
differentiate :CD4+ (T-helper cells) and CD8+ (cytotoxic T cells)
Assist in the clearance of intracellular organisms, virally infected cells,
tumor;
*also implicated transplant rejection*
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