Exam (elaborations)
Pharmacology 5334 Module 2 Exam Questions and Complete Solutions Graded A+
- Course
- Institution
Pharmacology 5334 Module 2 Exam Questions and Complete Solutions Graded A+
[Show more]
Content preview
Pharmacology 5334Module 2 Exam
Questions and Complete
Solutions Graded A+
Denning [Date] [Course title]
,Treatment of choice for oral therapy of UTI's - Answer: TMP/SMZ for 3 days; Nitrofurantoin for 5 days
Second line drugs for UTI - Answer: Ciprofloxacin and levofloxacin for 3 days
Nitrofurantoin - Answer: Urinary tract antiseptic
Nitrofurantoin uses - Answer: Lower UTI's; prophylaxis; recurrent lower UTI's. (not absorbed
systemically: cannot be used for anything in the kidneys)
Nitrofurantoin adverse effects - Answer: GI effects; pulmonary reactions; hematologic effects;
peripheral neuropathy (demyelination and nerve degeneration can occur and may be irreversible);
hepatotoxicity; birth defects
Methenamine - Answer: Decomposes to formaldehyde and ammonia; used for chronic lower UTI's;
contraindicated in renal and liver failure; drug interactions - urinary alkalinizers, which reduce effects,
sulfonamides pose risk for crystalluria
Acute cystitis treatment - Answer: Single dose therapy: fosfomycin; short-course therapy: TMP/SMZ for
3 days; conventional therapy: nitrofurantoin for 7 days
Acute uncomplicated pyelonephritis treatment - Answer: First line: TMP/SMZ, ciprofloxacin, and
levofloxacin for 10-14 days; second line: augmentin, cephalexin
Complicated UTI treatment - Answer: TMP/SMZ for 7-14 days, ciprofloxacin for 7-14 days, levofloxacin
for 5-14 days, augmentin for 7-14 days, cephalexin for 7-14 days
Recurrent UTI treatment - Answer: Prophylaxis with TMP/SMZ 3 times weekly for 6 months; TMP at
bedtime for 6 months; OR nitrofurantoin at bedtime for 6 months
Acute bacterial prostatitis treatment - Answer: -floxacins for 2-4 weeks
, Evaluation of drug sensitivity - Answer: Best done with sputum culture (takes up to 16 weeks for
results); drugs are chosen by patterns of drug resistance in the community and immunocompetence of
the patient; a new automated TB assay can identify sensitivity to rifampin in 2 hours and confirm the
presence of M. tuberculosis
Multi-drug resistant TB (MDR-TB) - Answer: Resistant to both isoniazid and rifampin
Extremely drug-resistant TB (XDR-TB) - Answer: Resistant to isoniazid and rifampin, all fluoroquinolones,
and at least one of the injectable second-line drugs
First line treatment of TB - Answer: Isoniazid, rifampin, pyrazinamide, and ethambutol. Rifapentine and
rifabutin are also considered to be first line
Two phases of TB treatment - Answer: Induction phase: lasts about 8 weeks, eliminate actively dividing
tubercle bacilli. Continuation phase: lasts from 18 weeks to 24 months, eliminate intracellular persisters
Drug sensitive TB treatment - Answer: 8 weeks induction of isoniazid, rifampin, pyrazinamide, and
ethambutol; continuation 18 weeks with isoniazid and rifampin
Isoniazid-resistant TB treatment - Answer: Rifampin, ethambutol, and pyrazinamide for 6 months
Rifampin-resistant TB treatment - Answer: Isoniazid, ethambutol, and pyrazinamide for 18-24 months
MDR-TB and XDR-TB treatment - Answer: 24 months with 2nd and 3rd line drugs; poor prognosis
Patients with TB plus HIV - Answer: More aggressive therapy required; minimum 6 months of
treatment; rifampin accelerates metabolism of antiretroviral therapy drugs and decreases their effects
Promoting drug adherence in TB patients - Answer: Directly Observed Therapy (DOT) - also allows for
ongoing assessment of clinical signs; intermittent dosing: 2-3 times/week
Latent TB tests - Answer: TB skin test; interferon Gamma Release Assays
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller YourExamplug. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $13.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
79223 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now