Antineoplastic
Drugs with
NCLEX Questions
and answers
What are characteristics of cell cycle--
nonspecific (CCNS) antineoplastic drug?
Effect cells randomly at any point of the cell
cycle
Great for treatment of slow growing cancer
that have many cells in the resting phase
When giving a patient a Alkylating drug what
adverse effects should you report to the
provider?
Report ringing or roaring in the ear-- possible
ototoxicity
, Report tingling, numbness, or pain in the
extremities-- peripheral neuropathy may
occur
Define extravasation
leakage of IV being infused to surrounding
tissue
What are serious side effects of
extravasation of chemotherapy?
Chemo drugs can damage tissue and cause
necrosis
Can lead to amputation
Not as likely with the use of Central lines
If you suspect Extravasation of
chemotherapy, what should you do?
stop the infusion immediately and contact
the prescriber--- leave the IV catheter in
place
Aspirate any residual drug or blood from the
catheter
Consult guidelines or the pharmacist
regarding antidotes, application of hot or
cold packs or sterile occlusive dressings, and
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