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Chapter 43_ Antiulcer Drugs Questions &Exam (elaborations) answers 100% satisfaction guarantee
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STUVIA 2024/2025Chapter 43: Antiulcer Drugs
A female patient with a peptic ulcer asks the nurse if misoprostol would be a good option for her
because it works well for her mother. Upon review of her medication list it is noted that she takes a
prenatal vitamin daily. What will the nurse do?
a. Recommend use of misoprostol since it works well for her mother.
b. Explain to the patient that misoprostol is contraindicated during pregnancy and for women of
childbearing age.
c. Tell the patient to purchase misoprostol over the counter.
d. Tell her that misoprostol is just another PPI and that she should just purchase a PPI that is
available over the counter. - ✔✔ANS: B
Misoprostol is a synthetic prostaglandin analog that can be used to prevent and treat peptic ulcers,
particularly in people using high doses of NSAIDs. As a prostaglandin analog, misoprostol is
contraindicated during pregnancy and for women of childbearing age. Misoprostol is available by
prescription only.
A patient has been taking famotidine (Pepcid) 20 mg bid to treat an ulcer but continues to have pain.
The provider has ordered lansoprazole (Prevacid) 15 mg per day. The patient asks why the new drug
is necessary, since it is more expensive. The nurse will explain that lansoprazole:
%
a. can be used for long-term therapy.
b. does not interact with other drugs.
c. has fewer medication side effects.
d. is more potent than famotidine. - ✔✔ANS: D
Famotidine is a histamine2 (H2) blocker. When patients fail therapy with these agents, proton pump
inhibitors, which can inhibit gastric acid secretion up to 90% greater than the H2 blockers, are used.
Lansoprazole is not for long-term treatment and has drug interactions and drug side effects, as do all
other medications.
A patient is taking rabeprazole (Aciphex) 20 mg per day to treat a duodenal ulcer. After 10 days of
treatment, the patient reports that the pain has subsided. The nurse will counsel the patient to:
a. continue the medication for up to 4-8 total weeks of treatment.
b. reduce the medication dose by half.
c. stop taking the medication.
d. take the medication every other day. - ✔✔ANS: A
With treatment, ulcer pain may subside earlier, but the healing process may take 1 to 2 months.
Patients should be counseled to take the drug for the length of time prescribed. Reducing the dose or
taking less frequently is not recommended.
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, STUVIA 2024/2025
A patient reports experiencing flatulence and abdominal distension to the nurse. Which
over-the-counter medication will the nurse recommend?
a. Alka-Seltzer
b. Maalox
c. Simethicone
d. Tums - ✔✔ANS: C
Simethicone is an antigas agent. Maalox Gas contains simethicone, while regular Maalox does not.
The other products do not contain simethicone.
A patient who has been instructed to use a liquid antacid medication to treat gastrointestinal upset
asks the nurse about how to take this medication. What information will the nurse include when
teaching this patient?
a. Take a laxative if constipation occurs.
b. Take 60 minutes after meals and at bedtime.
c. Take with at least 8 ounces of water to improve absorption.
d. Take with milk to improve effectiveness. - ✔✔ANS: B
Since maximum acid secretion occurs after eating and at bedtime, antacids should be taken 1 to 3
%
hours after eating and at bedtime. Taking antacids with meals slows gastric emptying time and
causes increased gastrointestinal (GI) secretions. Patients should not self-treat constipation or
diarrhea. Patients should use 2 to 4 ounces of water when taking to ensure that the drug enters the
stomach; more than that will increase gastric emptying time. If possible, antacids should not be taken
with milk or foods high in vitamin D.
A patient who has been taking ranitidine (Zantac) continues to have pain associated with a peptic
ulcer. A noninvasive breath test is negative. Which treatment does the nurse expect the provider to
order for this patient?
a. Adding an over-the-counter antacid to the patient's drug regimen
b. A dual drug therapy regimen
c. Amoxicillin (Amoxil), clarithromycin (Biaxin), and omeprazole (Prilosec)
d. Lansoprazole (Prevacid) instead of ranitidine - ✔✔ANS: D
This patient does not have H. pylori ulcer disease, so dual and triple drug therapy with antibiotics is
not indicated. Patients who fail treatment with a histamine2 blocker should be changed to a proton
pump inhibitor (PPI) such as lansoprazole. PPIs tend to inhibit gastric acid secretion up to 90%
greater than the histamine antagonists.
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