100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Chapter 4_ Pharmacogenetics Questions &Exam (elaborations) answers 100% satisfaction guarantee $7.99   Add to cart

Exam (elaborations)

Chapter 4_ Pharmacogenetics Questions &Exam (elaborations) answers 100% satisfaction guarantee

 9 views  0 purchase
  • Course
  • Chapter
  • Institution
  • Chapter

Chapter 4_ Pharmacogenetics Questions &Exam (elaborations) answers 100% satisfaction guarantee

Preview 1 out of 3  pages

  • August 11, 2024
  • 3
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • Chapter
  • Chapter
avatar-seller
EXAMQA
STUVIA 2024/2025
Chapter 4: Pharmacogenetics
A patient is diagnosed with Stevens-Johnson syndrome and the provider thinks this is related to an
HLA B*1502 variant that resulted in drug toxicity. The nurse would know that which of the following
medications is likely to blame:
a. Warfarin
b. Carbamazepine
c. Codeine
d. Irinotecan - ✔✔ANS: B

Persons with the human leukocyte antigen (HLA) B*1502 variant should avoid using carbamazepine
due to increased risk of developing Stevens-Johnson syndrome or toxic epidermal necrolysis.
Persons of Asian descent are most likely to carry this genetic variant.

Codeine and tramadol are prodrugs that require metabolism by which enzyme prior to providing
analgesic relief?
a. CYP2C19
b. CYP3A4
c. CYP2D6
d. CYP1A1 - ✔✔ANS: C
%


Codeine and tramadol are prodrugs that do not exhibit analgesic properties until converted to active
drug by the CYP2D6 enzyme in the liver. Nearly 10% of the population lack this drug-metabolizing
enzyme and therefore do not achieve pain relief with codeine or tramadol.

Gregor Mendel is known for which of the following?
a. First explaining the difference between dominant and recessive genes in
inheritance.
b. Discovering the structure of DNA.
c. Mapping roughly 25,000 genes in human DNA.
d. Coining the term pharmacogenomics. - ✔✔ANS: A

Gregor Mendel was the first to explain the difference between dominant and recessive genes in
inheritance, using pea flowers as an example. Watson and Crick were the first to describe the
structure of DNA. The Human Genome Project was completed in 2003 based on the work of many
scientists.

The FDA recommends genetic testing of which of the following for patients prior to initiating abacavir
due to a risk of potentially fatal multiorgan hypersensitivity in 6-10% of users?
a. CYP2C19


stuvia

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller EXAMQA. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $7.99. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

80461 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$7.99
  • (0)
  Add to cart