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NURS 5334 PHARMACOLOGY exam with questions and answers 2024
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NURS 5334 PHARMACOLOGY exam with questions and answers 2024
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NURS 5334 PHARMACOLOGY exam with questions andanswers 2024
Name non cardio selective beta blockers - Propranolol
Nadolol
carvedilol
lobetalol
(ABEAM)Name cardio selective beta blockers - Acebutolol
Bisoprolol
Esmolol
Atenolol
Metropolol
(ABEAM)Cardio selective beta blocks used in - Hyperthyroid
decrease heart rate
migraines
pheochromocytoma(secrete large amounts of catecholamines)
glaucoma- decreases aqueous humor
Patients must be weaned from beta-blockers to prevent - rebound excitation
3. Name Indirect-acting adrenergic antagonists - clonidine, guanabenz, guanfacine,
methyldopa, methyldopate
Drug of choice for HTN in pregnancy - Methyldopa
Alpha 2 side effect - reflex tachycardia
movement disorder; d/t imbalance of dopamine & acetylcholine→results in degeneration
of neurons that supply dopamine to brain
Diagnosed based on cardinal dyskinesias - Parkinson's disease
can confirm diagnosis of PD by giving dose of - levodopa to see if symptoms improve
cardinal dyskinesias are abnormal, uncontrollable movements like - bradykinesia,
tremor at rest, rigidity, postural instability, tremor
Levodopa/Carbidopa are only effect around ? - 5 years and hold off long as possible
When given alone much dose not reach peripheral metabolism - Levoidopa
, This helps decrease metabolism so more can reach brain - Carbidopa
What affects the absorption of levoidopa/carbidopa - Food delay especially high protein
diet
COMT inhibitors are given with L/carbidopa to help off period to increase 1/2 life which
lengths time between off periods - Entacapone
Talcapone
-carpone
Dopamine receptor agonist used in moderated PD to postpone L/cabidopa therapy -
Pamipexole
Ropinirole
Pamipexole and Ropinirole side effects are - risk takes behavior like compulsive
spending, gambling ,eating
Initially given to PD for mild therapy MAOB inhibitors
1st line of therapy - Selegiline
Rasagiline
Do not give MAOB with SSRI's or TCA's because it can cause - Serotonin syndrome
Seen in patient with low acetylcholine levels and drug therapy in not curative -
Alzheimer's Disease
Nave 4 drugs approved for Alzheimer's disease
Cholinesterase inhibitors - Donepezil
galantamine
rivastigmine
neuronal receptor blocker- Memantine
Treatment of muscle spasms in Alzheimers with - Diazepam
Tizanidine
Cyclobenzaprine
Metaxalone-least sedation
Chlorzoxazone
All can cause
Diazepam
Tizanidine
Cyclobenzaprine
Metaxalone-least sedation
Chlorzoxazone - physical dependance
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