©PREP4EXAMS @2024 [REAL EXAM DUMPS] Wednesday, July 17, 2024 1:27 AM
NSG 170 Final Exam Prep Questions and Answers (100% Pass)
What class is filgrastim (Neupogen) - ✔️✔️colony stimulating factors
What is gene therapy? - ✔️✔️The use of genes to treat/ prevent disease . Only available via
clinical trials. Technology replaces abnormal genes for healthy genes and can repair
abnormal gene cells or alternating the amount of genes that can be activated. They kill cancer
cells by inserting genes that boost the immune system to destroy the cancer.
What class is epoetin alfa (Epogen) - ✔️✔️Erythropoiesis-stimulating agents
What is epoetin alfa (Epogen) used for? MOA - ✔️✔️Used to counteract the effects of
chemotherapy. Stimulates the production and release of reticulocytes from bone marrow. Has
anemic affects and treats a wide variety of cancer.
What is filgrastim (Neupogen) used for? MOA - ✔️✔️Reduces the time for neutrophil
recovery and duration of fever in patients undergoing chemotherapy to treat AML. Binding to
and stimulating immature neutrophils to invade and differentiate, also activates mature
neutrophils
What class is Ondansetron (Zofran) - ✔️✔️Serotonin (5-HT3) Receptor Antagonist
(Antiemetic)
What does Ondansetron (Zofran) do? MOA - ✔️✔️Blocks 5-HT3 receptors in the brain and
peripheral nervous system.
Nursing Considerations for Ondansetron (Zofran) - ✔️✔️If the patient is taking frequently,
monitor liver function and clotting ability closely.Monitor patient for serotonin syndrome(s/s
are mental status changes,tachycardia, diaphoresis,flushing, n/v, tremors, and muscle
rigidity). Correct any electrolyte imbalances before starting drug therapy to reduce risk of
cardiac arrhythmias.
Monitor EKG and cardiac function in patients who have a cardiac history.
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, ©PREP4EXAMS @2024 [REAL EXAM DUMPS] Wednesday, July 17, 2024 1:27 AM
What class is metoclopramide (Reglan) - ✔️✔️prokinetic agent (Antiemetic)
What does metoclopramide (Reglan) do? MOA - ✔️✔️Stimulates motility of the upper GI
tract, blocks dopamine receptors at the chemoreceptor trigger zone. Oral, IV, IM, and
intranasal
What are the nursing considerations for metoclopramide (Reglan) - ✔️✔️Administer 30
minutes before each meal and at bedtime. Monitor liver function and WBC counts Monitor
bowel sounds Monitor for parkinsonian extrapyramidal adverse effects that cause involuntary
movements of face, tongue, and extremities.
What are the contraindication for metoclopramide (Reglan) - ✔️✔️Avoid giving with other
CNS depressants, can increase blood glucose level
What class is dronabinol (Marinol) - ✔️✔️Cannabinoids (Antiemetic)
What does dronabinol (Marinol) do? MOA - ✔️✔️Potentiates the activity of cannabinoid
receptors in the brain
Nursing considerations for dronabinol (Marinol) - ✔️✔️Teach the patient to change positions
slowly to prevent dizziness (orthostatic HTN). Most effective when administered 1-3 hours
before chemotherapy. Monitor the patient for hypotension, hypertension, syncope, and
tachycardia. Monitor liver function for increase.
What class is promethazine (Phenergan) - ✔️✔️Phenothiazine-like Drugs (Antiemetic)
What does promethazine (Phenergan) do? MOA - ✔️✔️Competes with histamine for receptor
sites. This makes it effective at managing nausea and vomiting, but also causes sedation
because works on same sites as antihistamines, similar to Benadryl.
Nursing considerations for promethazine (Phenergan) - ✔️✔️Effects on laboratory values. May
increase blood glucose levels. May decrease WBC, platelet, and granulocyte counts. Teach
patients to avoid. extensive sunlight exposure and to use sunscreen . Monitor IV site closely
if giving IV due to extravasation if infiltration occurs. Teach patient to avoid alcohol while on
this medication
Contraindications for promethazine (Phenergan) - ✔️✔️Avoid giving with CNS depressants
and MAO inhibitors
What class is Busulfan, carboplatin, cisplatin - ✔️✔️Alkylating Agents (Chemo)
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, ©PREP4EXAMS @2024 [REAL EXAM DUMPS] Wednesday, July 17, 2024 1:27 AM
What does Busulfan, carboplatin, cisplatin do? MOA - ✔️✔️Interferes with DNA production,
causing cellular death. Nonspecific kills both cancerous & noncancerous cells. CONTAINS
PLATINUM
Nursing considerations for Busulfan, carboplatin, cisplatin - ✔️✔️Monitor lab work, CBC with
diff, Platelet, uric acid, kidney & liver function. Monitor: temperature & respiratory status
Assess neurological status. Contraindicated for patients with liver, kidney & GI disorders. Do
not use IVs or needles with aluminum for administration. monitor fluid/nutritional intake
from n/v
What class is Bleomycin, dactinomycin, doxorubicin, epirubicin - ✔️✔️Antitumor Antibiotics
What do you need to monitor when taking doxorubicin? - ✔️✔️monitor closely bc can cause
secondary acute myeloid leukemia, cardiomyopathy, and myocardial toxicity
What kind of bottle does Antitumor medication come in? - ✔️✔️Glass bottle
What does Bleomycin, dactinomycin, doxorubicin, epirubicin do? MOA - ✔️✔️Interferes with
the production and action of nucleic acid to inhibit DNA & RNA replication in cells which
cause cellular death.
Nursing considerations for Bleomycin, dactinomycin, doxorubicin, epirubicin - ✔️✔️Monitor
lab work:CBC with diff & BMP. Monitor Client:Cardiac, respiratory, and neurological
status.Monitor for bleeding, signs of infection, nutritional and fluid intake. Contraindicated
for patients with liver, kidney, cardiac, pulmonary and GI disease. Close monitoring of IV
site BC very caustic to vein.
What class is tamoxifen? - ✔️✔️Selective Estrogen Receptor Modulator (SERM)
What does Tamoxifen treat? - ✔️✔️breast cancer
What does tamoxifen do? MOA - ✔️✔️Helps block cancerous cells from utilizing the
hormones that promote growth and inhibits the body's ability to produce hormones that
promote growth in cancerous cells. AKA hormone therapy and used to tx breast cancer, given
PO and pt stays on med for a long period afterward to prevent from coming back.
Nursing considerations for tamoxifen - ✔️✔️Monitor lab work, CBC & serum calcium.
Monitor Client: Blood pressure & cardiovascular status because estrogen causes HTN, Signs
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