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Entdeckung des Penicilins
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Entdeckung des Penicilins, Geschichte und Bakterien hemmen
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Entdeckung des PenicillinsBegriffsklärung:
exponentielles Wachstum:
in gleichen Zeitabschnitten um denselben Faktor verändert
Antibiotika:
Medikamente spezifische gegen Bakterien
Antibiotika resistent:
Wenn Bakterien nicht auf Antibiotika reagieren
Multiresistent:
Gegen mehrere Antibiotika resistent.
• Hindern den Gebrauch der Erbinformation
• hemmen Aufbau bakterieller Zellwand
• hemmen Bildung von Proteinen
antibiotikaresistent: ermöglicht die Wirkung von Antibiotika abzuschätzen oder zu neutralisieren.
Mögliche Nebenwirkung: Verdauungsproblemen (Übelkeit, Völlegefühl und Durchfall) allergische
Reaktion (Rötungen und Juckreiz)
Geschichte:
• Flemming schottisch
• Schimmelpilz töten Bakterien ab (hemmen den Wachstum)
• Massenweise in den USA hergestellt im WW2
• später Nobelpreis bekommen
• Soldaten sterben wegen bakterielle Infektion
• Desinfektionsmittel nutzt nicht
• 1941
Je größer Hemmhof, desto empfindlicher die Erreger
Verfahren zur Prüfung der Empfindlichkeit
Warum gibt es unterschiedliche Antibiotika?
• Unterschiedliche Bakterienstämme → Wirkungsweisen
• Empfindlichkeit oder Resistenz der Bakterien
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