- Blocks the reuptake of NE and DA into presynaptic neurons
- Appears to stimulate the cerebral cortex and subcortical structures
Amphetamine (Adderall) EA
A- ffects the dopaminergic and noradrenergic systems, causing the release of
neurotransmitters from storage sites at the central nervous system synapses
Amphetamine (Adderall) TU ADHD
Decreased appetite leading to weight loss
Growth problems?
Headache
Stomachache
Problems with sleep
Tics
Irritability and tearfulness - can be rebound
Amphetamine (Adderall) SE Anxiety/nervousness
Skin picking
Aggression
Black Box Warning: Risk of abuse/dependence
Adverse cardiac events
Hallucinations (tactile and visual usually)
Seizures
Mania/hypomania
PO
Once or twice daily
Amphetamine (Adderall) A
IR and XR
- Do not crush or chew XR
, 8/13/24, 11:16 AM
Other stimulants
Bupropion (Wellbutrin)
Antihypertensives
Amphetamine (Adderall) I
- Stimulant may decrease efficacy
TCAs
MAOIs
Take during the day
Drug holidays?
Signs/symptoms of abuse
Amphetamine (Adderall) monitor
Monitor HR, BP, and weight, mood, appetite, chest pain
Monitor growth and development
don't increase dose
Methylphenidate (Concerta) class Psychostimulant
- Blocks the reuptake of NE and DA into presynaptic neurons
- Appears to stimulate the cerebral cortex and subcortical structures
Methylphenidate (Concerta) EA
- Affects the dopaminergic and noradrenergic systems, causing the release of
neurotransmitters from storage sites at the central nervous system synapses
Methylphenidate (Concerta) TU ADHD
Decreased appetite leading to weight loss
Growth problems?
Headache
Stomachache
Problems with sleep
Tics
Irritability and tearfulness - can be rebound
Methylphenidate (Concerta) SE Anxiety/nervousness
Skin picking
Aggression
Black Box Warning: Risk of abuse/dependence
Adverse cardiac events
Hallucinations (tactile and visual usually)
Seizures
Mania/hypomania
PO
Once daily
Methylphenidate (Concerta) A
XR
- Do not crush or chew XR
Other stimulants
Bupropion (Wellbutrin)
Antihypertensives
Methylphenidate (Concerta) I
- Stimulant may decrease efficacy
TCAs
MAOIs
2/9
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