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NBME BRS Pathology HY Latest Update Questions and 100% Verified Correct Answers Actual Exam Guaranteed A+

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NBME BRS Pathology HY Latest Update Questions and 100% Verified Correct Answers Actual Exam Guaranteed A+

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  • August 13, 2024
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  • 2024/2025
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  • NBME BRS Pathology HY
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NBME BRS Pathology HY Latest Update 2024-
2025 250 Questions and 100% Verified Correct
Answers Actual Exam Guaranteed A+

"Worst headache of my life", vomiting, loss of consciousness, and blood in the CSF -
CORRECT ANSWER: Subarachnoid hemorrhage


100% chance of colon cancer by midlife - CORRECT ANSWER: Familial polyposis
syndromes


Caused by autosomal dominant mutations in the APC gene with hundreds of
adenomatous polyps carpeting the intestines


Abnormal proliferation of connective tissue of skin scars that results in large raised
tumor-like lesions - CORRECT ANSWER: Keloid


More common in African-Americans


Acute renal failure presenting as severe oliguria, causing death if untreated -
CORRECT ANSWER: Acute tubular necrosis


Tubules are capable of regeneration if basement membrane is intact


Alpha-1-antitrypsin deficiency - CORRECT ANSWER: Panacinar emphysema


Alpha-1-antitrypsin inhibits proteases, particularly elastase


Anti-parietal cell and anti-intrinsic factor antibodies with achlorhydria - CORRECT
ANSWER: Pernicious Anemia

,Parietal cells produce HCl and intrinsic factor; IF is required for vitamin B12 absorption
in the terminal ileum


Antimelanocyte antibodies associated with cell loss in discrete areas of skin -
CORRECT ANSWER: Vitiligo


Often associated with other autoimmune disease like pernicious anemia


Arthritis associated with monosodium urate crystals in metatarsophalangeal joints
(podagra) - CORRECT ANSWER: Gout


Crystal deposits from tophi


Assocated with folate deficiency during the initial weeks of gestation - CORRECT
ANSWER: Neural tube defects


alpha-fetoprotein level is elevated in maternal serum


Associated with asbestos exposure - CORRECT ANSWER: Malignant Mesothelioma


Neoplasm of visceral or parietal pleura or peritoneal neoplasm


Associated with berry aneurysms and subsequent subarachnoid hemorrhage -
CORRECT ANSWER: Adult polycystic kidney disease
(APKD)


Most common cystic disease of the kidney


Associated with cardiac amyloidosis, radiation injury, and sarcoidosis - CORRECT
ANSWER: Restrictive Cardiomyopathy

,Manifests as decreased ventricular filling owing to reduced ventricular compliance


Associated with cocaine abuse, alcohol abuse, and pregnancy; can also be idiopathic -
CORRECT ANSWER: Dilated cardiomyopathy


Heart may be 3 times heavier than normal with dilation of all four chambers


Associated with SIADH and Cushing syndrome as paraneoplastic syndromes -
CORRECT ANSWER: Small cell carcinoma


Small cell carcinoma has the worst prognosis of bronchogenic carcinoma subtypes


Asterixis - CORRECT ANSWER: Hepatic (portosystemic) Encephalopathy


Flapping tremor and neurologic sign, caused by nitrogenous metabolites which cannot
be detoxified by the damaged liver


Atrophy and gross depigmentation of the dopamine-producing cells of the substantia
nigra and locus coeruleus - CORRECT ANSWER: Parkinson disease


Histologically characterized by Lewy bodies which are intracytoplasmic, eosinophilic
inclusions within neurons


Atrophy of the caudate, putamen, and globus pallidus - CORRECT ANSWER:
Huntington disease


Caudate atrophy leads to "bat wing" lateral ventricles

, Autosomal dominant disorder with multiple benign hamartomatous polyps and melanin
pigmentation of the oral mucosa, hands and genitals - CORRECT ANSWER: Peutz-
Jegher Syndrome


Ball-valve obstruction by left atrial mass - CORRECT ANSWER: Myxoma


Most common primary tumor of the heart in adults


Barrett esophagus is the only recognized precursor - CORRECT ANSWER: Esophageal
adenocarcinoma


Barrett esophagus = squamous to columnar metaplasia (specialized, intestinal type
epithelium) in the distal esophagus


Basement membrane thickening resulting from nonenzymatic glycosylation - CORRECT
ANSWER: Diabetic Nephropathy


Biliary tract disease commonly seen in association with ulcerative colitis - CORRECT
ANSWER: Primary sclerosing cholangitis


Histologically characterized by onion-skin fibrosis of bile ducts


Black-blue papule with irregular borders - CORRECT ANSWER: Malignant Melanoma


Depth of invasion correlates with prognosis


Bleeding with passage of grape-like structures, increased hCG, and rapid increase in
uterine size - CORRECT ANSWER: Hydatidiform mole


Similar presentation without uterine enlargement = choriocarcinoma

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