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CCEB - ENDOCRINE PATHOLOGY EXAM QUESTIONS AND ANSWERS
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CCEB - ENDOCRINE PATHOLOGY EXAMQUESTIONS AND ANSWERS
Cushing's Syndrome is a disease associated with a rise in circulating cortisol levels.
Causes of Cushing's Syndrome - ANSWER: Increased ACTH from ant pit
Iatrogenic for corticosteroid administration.
Pituitary adenomas
Complications of Cushing's Syndrome: ANSWER Osteoporosis
HTN
Heart illness.
The symptoms of Cushing's disease - ANSWER: moon face.
A buffalo hump
Purple striate
hyperglycemia
Muscle loss
Excess aldosterone - Conn's syndrome.
What happens with Conn's syndrome? - ANSWER: High potassium loss.
Sodium and water retention.
, Primary aldosteronism (conn's syndrome) - ANSWER Tumor within the zone
glomerulosa = elevated aldosterone
Secondary aldosteronism is caused by excessive consumption of Glycyrrhiza
Glabra.
Major hypokalemia.
Congenital Adrenal Hyperplasia (CAH) - ANSWER condition during prenatal
development in which the adrenal glands produce high levels of androgens;
sometimes associated with masculinisation of external genitalia in genetic females;
and sometimes associated with higher rates of masculine-stereotyped play in
genetic females.
Primary hyperparathyroidism - ANSWER Adenoma of parathyroid glands -> high
calcium, hypertension, and gastric ulcers
Secondary hyperparathyroidism - ANSWER hypocalcemia due to prolonged renal
failure (limited vitamin D hydroxylation)
Low serum calcium
Lab results of hyperparathyroidism - ANSWER Increase ALP
Increased PTH
Change in serum calcium (high with primary, low with secondary)
What distinguishes acromegaly from gigantism - ANSWER Acro: Excess GH after
epiphyseal plate closure.
Gigant - Excess GH before closure of the epiphyseal plate
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