Exam (elaborations)
7 Drugs for Viral and Retroviral Infections
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- Minnesota State University, Mankato
7 Drugs for Viral and Retroviral Infections
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Chapter 07: Drugs for Viral and Retroviral InfectionsMULTIPLE CHOICE
1. Which statement about antiviral drugs is true?
a. Antiviral drugs kill viruses by altering viral DNA.
b. Antiviral drugs work by stopping viral replication.
c. Antiviral drugs alter the host immune system.
d. Antiviral drugs are considered virucidal.
ANS: B
Antiviral drugs must enter the infected cell and act at the site of infection to be effective.
Antivirals do not kill the virus but rather stop viral reproduction. This action means that all
antivirals are only virustatic, not virucidal.
DIF: Cognitive Level: Remembering REF: p. 101
2. Which antiviral drug is only given by oral inhalation?
a. Acyclovir (Zovirax)
b. Zanamivir (Relenza)
c. Oseltamivir (Tamiflu)
d. Amantadine (Symmetrel) ANS: B
Zanamivir is given only by oral inhalation. Acyclovir is given intravenously or as an orally
swallowed drug. Oseltamivir and amantadine are swallowed orally.
DIF: Cognitive Level: Remembering REF: p. 102
, 3. Which antiviral drug is most likely to have more severe CNS side effects, including
worsening of glaucoma?
a. Acyclovir
b. Amantadine
c. Valacyclovir
d. Zanamivir ANS: B
Amantadine crosses the blood–brain barrier and concentrates in the brain tissues. None of the
other drugs concentrate in brain tissues.
DIF: Cognitive Level: Remembering REF: p. 102
4. A patient who is asymptomatic comes into the clinic complaining of being exposed to a
coworker who has flu. What drug would be most appropriate for this patient?
a. Flumadine (rimantadine)
b. Valtrex (valacyclovir)
c. Crixivan (indinavir)
d. Ziagen (abacavir) ANS: A
Flumadine (rimantadine) is used for prophylaxis and treatment of illness caused by various
strains of influenza virus.
DIF: Cognitive Level: Applying REF: p. 101
5. Which drug is the only approved treatment for RSV?
a. Ribavirin (Virazole)
b. Cidofovir (Vistide)
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