EPPP-Psychopharmacology All Answers Correct
Depression Types - Endogenous Depression: Depression with genetic or biological causes. - Exogenous Depression: Depression due to external causes (e.g., life events).
Antidepressants - Norpramin: Falls under the category of Tricyclic antidepressants (...
- Insomnia, anxiety, tremors, and frequent urination.
, - Sexual dysfunction.
- Common Side Effects of MAOIs:
- Insomnia, weight gain, dizziness, headache, and nausea.
- Anticholinergic effects similar to those noted above.
Drug Interactions and Overdose
- Hypertensive Crisis Symptoms: Intracranial bleeding, tachycardia, headache, shortness of breath,
severe anxiety.
- TCAs Overdose Symptoms: Ataxia, impaired concentration, agitation, severe hypotension, fever,
cardiac arrhythmias, delirium, seizures, and coma.
- Cardiotoxic Symptoms: Tachycardia, palpitations, severe hypotension (rapid BP drop), and cardiac
arrhythmia.
Mechanism of Action
- Agonists: Produce effects similar to those of natural neurotransmitters.
- Antagonists: Block or reduce the effects of neurotransmitters on their receptors without producing any
activity on their own.
- Inverse Agonists: Produce effects similar to natural neurotransmitters but are less potent.
Miscellaneous
- Paxil (paroxetine): Advantage over Prozac (fluoxetine) is that it causes less anxiety and anorexia.
- First Medication Used for Treating Depression: Tofranil.
- EPS (Extrapyramidal Symptoms) from SSRIs: Can include akathisia and parkinsonism.
- Steak: A meat that can usually be consumed without concerns regarding tyramine when taking MAOIs.
barbituates at receptor sites for gaba ✔️indirect agonist
attach at the binding site and interfere with the action of a neurotrans ✔️indirect antagonist
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