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USMLE UWORLD STEP 1 EXAM 2024/2025 WITH GUARANTEED ACCURATE ANSWERS |VERIFIED
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USMLE UWORLD STEP 1 EXAM 2024/2025 USMLE UWORLD STEP 1 EXAM 2024/2025 WITH GUARANTEED ACCURATE ANSWERS |VERIFIED Pt had part of his small bowel surgically removed due to bowel ischemia and is now receiving parenteral nutrition. He develops RUQ pain and N/V. Diagnosis? Pathogenesis? - ACC...

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  • August 15, 2024
  • 13
  • 2024/2025
  • Exam (elaborations)
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  • USMLE UWORLD STEP 1
  • USMLE UWORLD STEP 1

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USMLE UWORLD STEP 1 EXAM
2024/2025
USMLE UWORLD STEP 1 EXAM 2024/2025 WITH GUARANTEED ACCURATE
ANSWERS |VERIFIED




Pt had part of his small bowel surgically removed due to bowel ischemia and is
now receiving parenteral nutrition. He develops RUQ pain and N/V.


Diagnosis?
Pathogenesis? - ACCURATE ANSWER✅✅Cholesterol Gallstones


Form due to biliary/gallbladder stasis caused by decreased CCK release since
nutrition is not passing through the stomach/gut like normal


Standard Error (SE) vs. Standard Deviation (SD) - ACCURATE
ANSWER✅✅SE [= SD/sq.rt. (n)] is used to account for variability of sampling
(small sample sizes for studies) since an entire population is not studied at once

, Pt develops a gram-negative STI (Neisseria gonorrhoeae). The bacteria has an IgA
protease that splits IgA dimer (J chain). What is the role of this enzyme in the
infection? - ACCURATE ANSWER✅✅IgA antibodies bind to pili and
membrane proteins needed for bacterial adherence to mucosa, thus inhibiting
mucosal colonization. Thus, this enzyme facilitates mucosal adherance for the
bacteria.


16 y/o boy w/ mild intellectual disability is brought in for ADHD evaluation.
Parents said he had speech and motor delay as a child. PE shows a long narrow
face, prominent mandible & forehead, large testes, and joint hyperlaxity.


Diagnosis? Genetics? - ACCURATE ANSWER✅✅Fragile X Syndrome


X-linked (LOF mutation in FMR1 gene)


Clinical features are most apparent after puberty


What are the treatment options for Cyanide (CN) poisoning? MOA? - ACCURATE
ANSWER✅✅1. Nitrites (e.g. Amyl Nitrite)
MOA: induces methemoglobin formation (oxidizes ferrous iron to ferric iron),
which has a high affinity for CN so it sequesters it in the blood preventing it from
exerting its toxic effects on mitochondria


2. Sodium Thiosulfate
MOA: combines w/ CN to form the less toxic thiocyanate, which is excreted in the
urine


Cytosine deamination forms what base? What are the steps for DNA repair of this
type of damage? - ACCURATE ANSWER✅✅Cytosine deamination --> Uracil

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