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BASIC AND CLINICAL PHARMACOLOGY 14TH EDITION KATZUNG TREVOR TEST BANK COMPLETE TEST BANK ALL 64 CHAPTERS QUESTIONS WITH SOLUTIONS AND RATIONALES$14.99
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Basic and Clinical Pharmacology 14th Edition Katzung Trevor Test Bank
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FULL TESTBANK
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INSTANT DOWNLOAD!!
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TEST BANK n
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Basic and Clinical Pharmacology 14th Edition Katzung Trevor Test Bank
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Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1. A nurse working in radiology administers iodine to a patient who is having a
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computed tomography (CT) scan. The nurse working on the oncology unit
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administers chemotherapy to patients who have cancer. At the Public Health
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Department, a nurse administers a measles-mumps-rubella (MMR) vaccine
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toa 14-month-old child as a routine immunization. Which branch of
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pharmacology best describes the actions of all three nurses?
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A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are
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involved with clinical pharmacology or pharmacotherapeutics, which is a
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branch of pharmacology that deals with the uses of drugs to treat, prevent,
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and diagnose disease. The radiology nurse is administering a drug to help
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diagnose a disease. The oncology nurse is administering a drug to help treat
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adisease. Pharmacoeconomics includes any costs involved in drug therapy.
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Pharmacodynamics involves how a drug affects the body n n n n n n n
andpharmacokinetics is how the body acts on the body.
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2. A physician has ordered intramuscular (IM) injections of morphine, a
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narcotic, every 4 hours as needed for pain in a motor vehicle accident
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victim.The nurse is aware this drug has a high abuse potential. Under what
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categorywould morphine be classified?
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A) Schedule I n
B) Schedule II n
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C) Schedule III n
D) Schedule IV n
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II drugs
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because of severe dependence liability. Schedule I drugs have high abuse
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potential and no accepted medical use. Schedule III drugs have a lesser
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abuse potential than II and an accepted medical use. Schedule IV drugs
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havelow abuse potential and limited dependence liability.
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3. When involved in phase III drug evaluation studies, what
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responsibilitieswould the nurse have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate patients to be involved in the drug study
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C) Monitoring and observing patients closely for adverse effects n n n n n n n
D) Conducting research to determine effectiveness of the drug n n n n n n n
Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in
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whichpatients are asked to record any symptoms they experience while
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taking thedrugs. Nurses may be responsible for helping collect and analyze
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the information to be shared with the Food and Drug Administration (FDA)
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butwould not conduct research independently because nurses do not
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prescribe medications. Use of animals in drug testing is done in the
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preclinical trials. Select patients who are involved in phase II studies to
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participate in studies where the participants have the disease the drug is
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intended to treat. These patients are monitored closely for drug action and
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adverse effects. Phase I studies involve healthy human volunteers who are
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usually paid for their participation. Nurses may observe for adverse effects
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and toxicity.
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4. What concept is considered when generic drugs are substituted for
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brandname drugs?
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A) Bioavailability
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B) Critical concentration n
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailability is the portion of a dose of a drug that reaches the systemic n n n n n n n n n n n n n
circulation and is available to act on body cells. Binders used in a generic
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drug may not be the same as those used in the brand name drug. Therefore,
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the way the body breaks down and uses the drug may differ, which may
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eliminate a generic drug substitution. Critical concentration is the amount
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ofa drug that is needed to cause a therapeutic effect and should not differ
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between generic and brand name medications. Distribution is the phase of
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pharmacokinetics, which involves the movement of a drug to the bodys
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tissues and is the same in generic and brand name drugs. A drugs half-life
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isthe time it takes for the amount of drug to decrease to half the peak level,
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which should not change when substituting a generic medication.
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5. A nurse is assessing the patients home medication use. After listening to
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thepatient list current medications, the nurse asks what priority question?
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A) Do you take any generic medications?
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B) Are any of these medications orphan drugs?
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C) Are these medications safe to take during pregnancy?
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D) Do you take any over-the-counter medications?
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Ans: D
Feedback:
It is important for the nurse to specifically question use of over-the-counter
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nmedications because patients may not consider them important. The patient
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nis unlikely to know the meaning of orphan drugs unless they too are health
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ncare providers. Safety during pregnancy, use of a generic medication, or
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nclassification of orphan drugs are things the patient would be unable to n n n n n n n n n n n
nanswer but could be found in reference books if the nurse wishes to
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nresearchthem. n
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