100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Test Bank for Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, 9781259641152, Covering Chapters 1-66 | Includes Rationales $17.99   Add to cart

Exam (elaborations)

Test Bank for Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, 9781259641152, Covering Chapters 1-66 | Includes Rationales

 5 views  0 purchase
  • Course
  • Institution
  • Book

Test Bank for Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, 9781259641152, Covering Chapters 1-66 | Includes Rationales

Preview 2 out of 6  pages

  • August 17, 2024
  • 6
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
avatar-seller
Test Bank for Basic and Clinical Pharmacology, 14th Edition by
Bertram G. Katzung, 9781259641152, Covering Chapters 1-66
| Includes Rationales


Treatment of superficial fungal infections caused by dermatophytic fungi may be accomplished with
the use of? - ANSWER: 1. topical antifungal agent
2. oral antifungal agent

Examples of Topical Antifungal Agents - ANSWER: clotrimazole, efinaconazole, econazole,
ketoconazole, luliconazole, miconazole, oxiconazole, sertaconazole, sulconazole, ciclopirox olamine,
naftifine, terbinafine, butenafine, and tolnaftate

Examples of Oral Antifungal Agents - ANSWER: griseofulvin, terbinafine, fluconazole, and itraconazole

(AZOLE DERIVATIVES) Topical imidazoles are: - ANSWER: clotrimazole, econazole, ketoconazole,
luliconazole, miconazole, oxiconazole, sertaconazole, and sulconazole

Topical imidazole coverage - ANSWER: wide range of activity against:
Dermatophytes (Epidermophyton, Microsporum, and Trichophyton)

and

Yeasts, including Candida albicans and Pityrosporum orbiculare

Topical imidazole coverage - ANSWER: Dermatophytes and yeasts

Topical imidazoles used in vulvovaginal candidiasis? - ANSWER: Miconazole and Clotrimazole

available as a cream or lotion and as vaginal cream or suppositories - ANSWER: Miconazole

available as a cream or lotion and as vaginal cream and tablets - ANSWER: Clotrimazole

treatment of onychomycosis of the toenails - ANSWER: Efinaconazole (EFIctive for onychomycosis)

How long is the medication for onychomycosis using Eficonazole? - ANSWER: 48 weeks

available as a cream and lotion for topical use - ANSWER: Econazole and Oxiconazole

available as a cream for topical treatment of dermatophytosis and candidiasis and as a shampoo or
foam for the treatment of seborrheic dermatitis. - ANSWER: Ketoconazole

treats dermatophytosis, candidiasis and seborrheic dermatitis? - ANSWER: Ketoconazole

available as a cream - ANSWER: Luliconazole and Sertaconazole

available as a cream or solution - ANSWER: SULConazole (SULotion & Cream)

Why are topical antifungal-corticosteroid fixed combinations have been introduced? - ANSWER: to
provide more rapid symptomatic improvement than an antifungal agent alone.

2 is better than 1.

, Example of topical antifungal-corticosteroid fixed combination? - ANSWER: Clotrimazole-
betamethasone

How frequent do you need to apply certain topical antifungals to clear specific fungal infections? -
ANSWER: 1x- or 2x-daily : clears superficial dermatophyte (for 2-3 wks using any of antifungals)

2x daily : clears seborrheic dermatitis (w/ ketoconzaole)

3x or 4x daily : clears paronychial and intertriginous candidiasis

AE of topical imidazoles? - ANSWER: stinging, pruritus, erythema, and local irritation.

Allergic contact dermatitis is uncommon.

This is a synthetic broad-spectrum antimycotic agent - ANSWER: Ciclopirox olamine

Coverage of Ciclopirox olamine? - ANSWER: activity against dermatophytes, Candida species, and P
orbiculare.

MOA of Ciclopirox olamine? - ANSWER: inhibits the uptake of precursors of macromolecular synthesis

Site of action of Ciclopirox olamine? - ANSWER: probably the fungal cell membrane.

treatment of dermatomycosis, candidiasis, and tinea versicolor - ANSWER: Ciclopirox olamine (1%
cream)

treatment of mild to moderate onychomycosis of fingernails and toenails? - ANSWER: Ciclopirox
olamine (8% cream)

1-2% of the dose is absorbed when applied as a solution at what part of the body? - ANSWER: on the
back under an occlusive dressing.

AE of Ciclopirox olamine? - ANSWER: Pruritus and worsening of clinical disease have been reported.
The potential for allergic contact dermatitis is small.

is the first oxaborole antifungal drug approved for the treatment of toenail onychomycosis. -
ANSWER: Tavaborole

MOA of Tavabarole? - ANSWER: blocks fungal protein synthesis by inhibiting aminoacyl-transfer
ribonucleic acid synthetase.

treatment of toenail onychomycosis - ANSWER: Tavaborole (5% solution) 1x daily for 48 weeks

are allylamines that are highly active against dermatophytes but less active against yeasts. - ANSWER:
Naftifine hydrochloride and terbinafine

Naftifine hydrochloride and terbinafine coverage? - ANSWER: Dermatophytes

Can Naftifine hydrochloride and terbinafine clear infections caused by yeast? - ANSWER: No. It is only
active against Dermatophytes

MOA of Naftifine hydrochloride and terbinafine? - ANSWER: selective inhibition of squalene
epoxidase, a key enzyme for the synthesis of ergosterol

treatment of dermatophytosis? - ANSWER: Naftifine hydrochloride and terbinafine (1% creams) 2x
daily for 1-2 weeks

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller phinta004. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $17.99. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

67096 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$17.99
  • (0)
  Add to cart