MCBM Exam #2: Horovorka Questions
and Answers 100% Verified
What do all connective tissues have in common? - ANSWER - Vast extracellular matrix
What are the 4 main types of connective tissue? - ANSWER - Cartilage, Bone, Blood, and
Connective Tissue Proper
Is cartilage vascular or avascular? - ANSWER - Avascular
What secretes the extracellular matrix in connective tissue? - ANSWER - Fibroblasts
What is the difference between dense regular and dense irregular connective tissue? What do
they form? - ANSWER - Regular: forms tendons, ligaments, and aponeuroses. Collagen
bundles are arranged in parallel orientation, giving the tissue greater tensile strength.
Irregular: Forms the capsules of solid organs, the submucosa of hollow organs, and the reticular
layer of skin. Oriented in different directions, allows resistance to excessive stretching.
What is the extracellular matrix composed of? - ANSWER - Ground substance and Fibers
What is the purpose of ground substance? - ANSWER - Provides compressive resistance,
flexibility, and can be a biochemical barrier.
What usually makes up ground substance? - ANSWER - Water, proteoglycans/glycoproteins
(proteins with covalently attached polysaccharides), and glycosaminoglycans (Long unbranched
polysaccharides)
What is the most important glycosaminoglycan in ground substance? What charge does it
have? What is the result? - ANSWER - Hyaluronic Acid, has a negative charge which draws in
water.
, What is the difference between elastin and fibrilin? - ANSWER - Elastin: Protein with alternating
hydrophilic alpha-helical domains and hydrophobic random coil domains, cross-linked within
extracelluar matrix.
Fibrilin: Glycoprotein that forms structural support for the elastic fibers. Sensitive to UV rays
(causes extra wrinkley people)
Where will we see fibroblasts most prominently? How do they appear? - ANSWER - Dense
Connective Tissue, we just see their nuclei since their cytoplasm is squished.
What cell types will we see in loose connective tissue? How will it appear on a stain? What does
it form? - ANSWER - Contains fibroblasts, mast cells, macrophages, and leukocytes.
What is collagen (generally)? - ANSWER - Glycoprotein with sugars attached to hydroxylized
amino acids.
What amino acids are being hydrolyzed? - ANSWER - Proline and Lysine
What is tropocollagen? - ANSWER - A structural component of collagen formed by 3 chains of
amino acids to form a triple helix.
Tropogollagen is made up of 3 different chains of collagen. Are the 3 chains the same? -
ANSWER - All three can be the same, there may be two types, or all different types!
What are collagen fibrils formed from? How are they oriented? - ANSWER - They are formed
from polymerized tropocollagen molecules. They are oriented head to tail in parallel fashion.
What are collagen fibers? What kind of imaging can they be seen by? - ANSWER - They are
groups of fibrils large enough to be seen by light microscopy.
What are the different types of collagens? Where are they found? - ANSWER - Type 1:
Connective Tissue Proper and Bone
Type 2: Cartilage
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller NursingTutor1. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $10.99. You're not tied to anything after your purchase.
