Exam (elaborations)
Janeways Immunobiology 9th Edition by Kenneth Murphy; Casey Weaver |
- Course
- Institution
- Book
Janeways Immunobiology 9th Edition by Kenneth Murphy; Casey Weaver |
[Show more]
Connected book
Book Title:
Author(s):
- Edition:
- ISBN:
- Edition:
More summaries for
-
Janeways Immunobiology 9th Edition by Kenneth Murphy; Casey Weaver |
-
Janeways Immunobiology 9th Edition by Kenneth Murphy; Casey Weaver |
-
Apunte Inmunología Veterinaria
1 review
By: tutorsection1 • 1 month ago
Seller
Follow
phinta004
Reviews received
Content preview
Test bank for Janeways Immunobiology 9th Edition byKenneth Murphy; Casey Weaver | 9780815345053 | Chapter
1-16 | All Chapters with Answers and Rationals
Lectin - ANSWER: Carbohydrate-binding antimicrobial peptide. Includes RegIIIgamma and human
RegIIIalpha
Humoral fluid - ANSWER: Complement and other defensive proteins circulating in bodily fluid
5 categories of disease-causing agents - ANSWER: Bacteria, virus, fungi, helminth, protozoa
Composition of Gram positive bacterial cell wall - ANSWER: Peptidoglycan, Lipoteichoic acid, Teichoic
acid.
Composition of Gram negative bacterial cell wall - ANSWER: Smaller peptidoglycan, Lipoprotein,
Lipopolysaccharide
Zoonotic Infection - ANSWER: Disease originally endemic in non-human animals.
Cystic Fibrosis - ANSWER: Loss of function of epithelial chloride channel, causing dehydrated mucus.
Bacterial colonies typically form as epithelial cilia fail to move mucus out of body.
Function of lysozyme - ANSWER: Cleaves carbohydrate bonds in peptidoglycan layer of bacterial cell
walls.
Where are lysozyme and secretory phospholipase A2 found? - ANSWER: Tears, saliva, paneth cells of
small intestine.
Secretory phospholipase A2 - ANSWER: Basic enzyme that can enter bacterial cell wall to hydrolyze
phospholipids in plasma membrane.
Defensin structure - ANSWER: Amphipathic polypeptide.
Function of defensin proteins - ANSWER: Insert into hydrophobic region of membrane bilayer,
forming a pore upon contact with other inserted defensins.
Paneth cell locatied - ANSWER: Small intestinal crypts
Zymogen - ANSWER: Inactive enzyme precursor requiring hydrolysis of pro-region
Neutrophil primary granules - ANSWER: Lysosome-like vesicle containing antimicrobial agents.
Induced to fuse with phagosome. Contains neutrophil elastase
Neutrophil secondary granules - ANSWER: Store propeptide cathelicidins; activated upon fusion
w/primary granule.
Cathelicidins - ANSWER: Antimicrobial protein produced by neutrophil and macrophages, secreted by
keratinocytes and epithelia of lung and intestine.
Histatins - ANSWER: Produced in parotid, sublingual and submandibular glands. Are antifungal
peptides that promote rapid wound healing.
Complement proteins are produced mostly in the ________________ - ANSWER: Liver
, 3 pathways of complement activation - ANSWER: Classical, alternative, lectin
Binds to antigen:antibody complex and pathogenic surface - ANSWER: C1q
binds to carbohydrate structures (ex. mannose) - ANSWER: MBL/Ficolins
Properdin (factor P)
Activating enzymes - ANSWER: C1r
C1s
C2a
Bb
D
MASP-1, 2, 3
Surface-binding proteins and opsonins - ANSWER: C3b
C4b
Inflammatory mediators - ANSWER: C3a
C4a
C5a
Membrane-attack proteins - ANSWER: C5b
C6
C7
C8
C9
Complement receptors - ANSWER: CR1
CR2
CR3
CR4
CRIg
C3 convertase of lectin pathway - ANSWER: C4b2a
C3 convertase of classical pathway - ANSWER: C4b2a
C3 convertase of alternative pathway - ANSWER: C3bBb
Fluid phase C3 convertase - ANSWER: C3(H2O)Bb
Protein that stabilizes alternative and fluid phase convertase - ANSWER: Properdin (Factor P)
Surfactant protein SP-A and SP-D - ANSWER: Secreted in lung epithelia. Opsonize pathogens, but do
not interact with MASP and so do not activate complement
The pathogen sensor of the classical pathway - ANSWER: C1 complex
C1 activated by - ANSWER: Surface-bound antibody, direct pathogen surface.
C1 pathogen sensor subunit - ANSWER: C1q
C1 serine protease subunits - ANSWER: C1r and C1s (initially inactive)
Proteoglycan - ANSWER: Component of animal ECM in connective tissue
Peptidoglycan - ANSWER: Component of bacterial cell wall
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller phinta004. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $17.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
52510 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now