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phm exam 1 questions with complete solutions
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phm exam 1 questions with complete solutions
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phm exam 1 questions with complete solutionsa drug that has high affinity for cholinergic receptors in
autonomic ganglia junction and that is used to reduced bleeding
during surgery Correct Answers trimethaphan
A drug which causes "cardiac depression" by actions in the heart
and which would also antagonize the effect of isoproterenol on
blood vessel diameter in the vasculature of skeletal muscle
Correct Answers propranolol
a drug which has low affinity for muscarinic and nicotinic
cholinergic receptors but is considered a cholinomimetic
Correct Answers pyridostigmine
a drug which is a pharmacological agonist but which produces
blockade of synaptic transmission at skeletal neuromuscular
junction Correct Answers succinylcholine
a patient is given drug to relieve pain - this effect requires the
drug to act as an agonist. When given repeatedly over a period
of several days, this drug also induces the liver enzyme which
metabolizes this drug. Given this information, which of the
following is most likely to occur? Correct Answers a rightward
shift of the dose-response relationship for the drug
a pharmacological antagonist at a particular time of receptor
Correct Answers will bind to but not activate those receptors
will have physiological or clinical efficacy
, activation of the renin-angiotensin system: Correct Answers
will occur if BP decreases
will be reduced or prevented by B1 adrenoreceptor antagonists
an appropriate drug to reverse the direct cardiac effects of
atropine overdose Correct Answers physostigmine
atracurium is used to produce relaxation of skeletal muscle
during surgery and other procedures. atracurium enters this
effected by Correct Answers blocking the binding of
acetylcholine binding to cholinergic receptors on the muscle
fibers
bethanechol is preferred clinically over acetylcholine to cause
therapeutic actions in the bladder because Correct Answers
acetylcholine but not bethanechol is rapidly metabolized by
enzymes in the plasma
Bethanechol: Correct Answers is a choline ester that is also a
cholinomimetic
has high affinity for muscarinic cholinergic receptors
considering that there is ongoing activity in both the
parasympathetic nervous system and the sympathetic nervous
system, atenolol will produce: Correct Answers decreased heart
rate through actions in the heart
cyclopentolate is Correct Answers a muscarinic receptor
antagonist
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