When developing a new drug what is the correct order of testing? Correct Answer: In Vitro preclinical and clinical How often does the animal welfare regulations require the IACUC to review and do inspections of the facilities? Correct Answer: At least every six months Which of the agencies regulate...
LAT PRACTICE EXAM 2022|QUESTIONS WITH
COMPLETE SOLUTIONS
,LAT PRACTICE EXAM 2022|QUESTIONS WITH
COMPLETE SOLUTIONS
When developing a new drug what is the correct order of testing? - Correct Answer-In
Vitro preclinical and clinical
How often does the animal welfare regulations require the IACUC to review and do
inspections of the facilities? - Correct Answer-At least every six months
Which of the agencies regulates disinfectants and sterilizers used on hard surfaces? -
Correct Answer-United States and environmental protection Agency
What type of floor plan is designed so each room has exit doors to a
Dirty corridor that wraps around the periphery of the floor plan? - Correct Answer-Three-
corridor
What is a biofilm? - Correct Answer-Microrganism build-up on tank wall
What substance can be added to an aquatic system to raise pH? - Correct Answer-
Sodium bicarbonate
Which parameter is a measure of both calcium and magnesium ions in water? - Correct
Answer-Total hardness
AWR (enforced by USDA) require IACUC have how many members? - Correct Answer-
A tleast 3.
Chairperson,vet,and a member not associated with inst.
PHS policy requires how many IACUC members? - Correct Answer-At least 5.
Chairperson,vet,scientist,nonscientist, and community member.
Nonfederal research facilities must register with USDA if species are covered by? -
Correct Answer-AWA. Updates every 3 yrs. signed by IO.
Inst. housing USDA Covered animals must submit a report how often to the USDA? -
Correct Answer-Annually
(PHS)
Public health service - Correct Answer-Publishes the policy on the humane care and
use of laboratory animals.
(AAALAC)
Association for Assessment and Accreditation of Laboratory Animal Care International -
Correct Answer-Provides peer evaluation of animal care and use programs
(AWR)
, LAT PRACTICE EXAM 2022|QUESTIONS WITH
COMPLETE SOLUTIONS
Animal welfare regulation - Correct Answer-Describes what a facility must do to comply
with the AWA
(FDA)
Food and drug administration - Correct Answer-Requires compliance with the good
laboratory practices (GLPs)
(USDA)
U.S. Department of agriculture - Correct Answer-Registers institutions using species
covered by animal welfare act
What two federal agencies require compliance with the GLPs? - Correct Answer-
(EPA)environmental protection agency and (FDA) food and drug admin.
How often must insitutions update registration with USDA if using AWA species? -
Correct Answer-Every 3 yrs
What agency enforces the PHS policy? - Correct Answer-(OLAW)
Office of laboratory animal welfare
What document is signed by IO and is filed to commit the institution to compliance with
the PHS policy? - Correct Answer-Animal welfare assurance
What animals are covered under the PHS policy? - Correct Answer-ALL vertebrates
USDA covered animals submit a report to the USDA how often? - Correct Answer-
Annually
USDA covered species may only be approved for how long? - Correct Answer-1 year
USDA vet med officers (VMO) conduct unannouced ispections how often? - Correct
Answer-Atleast annually
IACUCs are mandated by what? - Correct Answer-Federal mandate
What is a quality assurance unit responsible for ensuring compliance with? - Correct
Answer-GLP
Which organization uses the GUIDE as one of its standards for accreditation of Lab
animal programs? - Correct Answer-AAALAC
Most aquatic tanks are made of what plastic? - Correct Answer-Polycarbonate and
polysulfone
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