Germ Theory of Disease proposes that microorganisms are the cause of many diseases
Giralamo Fracastoro proposed in 1545 that epidemic diseases were caused by transferable tiny particles or "tinder" that could transmit infection by contact.
Agostino Bassi discovered in 1807 that muscardine disease...
MCB 100 Exam 1 Questions and
Solutions
Germ Theory of Disease ✅proposes that microorganisms are the cause of many
diseases
Giralamo Fracastoro ✅proposed in 1545 that epidemic diseases were caused by
transferable tiny particles or "tinder" that could transmit infection by contact.
Agostino Bassi ✅discovered in 1807 that muscardine disease of silkworms was
caused by living parasitic organism (fungus, Beauveria bassiana) and in 1884 proposed
that human diseases (syphilis, plague) were also caused by living microorganisms
Fredrich Henle ✅developed the concepts of contagium vivum and contagium
animatum in his essay "Von den Miasmen und Kontagien" in 1840 (miasma = "bad air")
- early germ theory that living organisms caused infectious diseases
Ignaz Semmelweis ✅made the connection between lack of hand washing and
childbirth (puerperal) fever in 1847. Making doctors wash hands with chlorinated lime
water reduced mortality from childbirth fever from 18% to 2% at his hospital
John Snow ✅traced the source of a cholera outbreak in London in 1854 to
contaminated water obtained from a particular well, which was at the geographical
center of the outbreak - this work laid the foundation for the field of epidemiology, which
investigates the occurrence, spread, and distribution of infectious disease.
Louis Pasteur ✅conducted the first experiments demonstrating that fermentation and
growth of microbes in nutrient broth did not proceed by spontaneous generation of by
miasma (bad air) - two prevailing theories at the time. Importantly, he was able to
convince most of Europe at the time. His research showed that microbes caused beer,
wine, and milk to spoil and he invented the process of pasteurization in 1862.
Basic principal of microscopy ✅Microscopy involves the generation of a magnified
image from the original sample in order to resolve objects that cannot be resolved by
the human eye.
Resolution (resolving power) ✅Ability to distinguish two points that are close together.
The better the resolution, the better two nearby objects are distinguished from one
another. Different types of microscopes have different resolving powers.
Taxonomy ✅consists of classification, nomenclature, and identification of different
organisms
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