8. Hypoxemia, polycythaemia, hypercapnia - ANS ✓Blue bloater
(chronic bronchitis)
9. Indurated, ulcerated genital lesion - ANS ✓Nonpainful = syphilis.
Painful with exudate = chancroid
10. Infant with failure to thrive, hepatosplenomegaly,
neurodegeneration - ANS ✓Niemann-Pick disease (genetic
sphingomyelinase deficiency)
11. Infant with hypoglycaemia, failure to thrive, and
hepatomegaly - ANS ✓Cori's disease (debranching enzyme
deficiency, no glycogenolysis) or Von Gierke's
12. Infant with microcephaly, rocker-bottom feet, clenched
hands, and structural heart defect - ANS ✓Edward's syndrome
(Trisomy 18)
20. Necrotizing vasculitis (lungs) and necrotizing GN - ANS
✓Wegner's (c-ANCA) and Goodpasture's (anti-GBM). Wegner's can
also have upper airway involvement
21. Neonate with arm paralysis following difficult birth.
Possible clavicle fx, probably large for gestational age - ANS
✓Erb-Duchenne palsy
22. No lactation postpartum, absent menstruation, cold
intolerance - ANS ✓Sheehan's syndrome
23. Nystagmus, intention tremor, scanning speech, also
bilateral internuclear ophthalmoplegia - ANS ✓MS (Charcot's)
24. Oscillating slow / fast breathing - ANS ✓Cheyne-Stokes
(central apnea from CHF or increased ICP)
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