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Lilleys Pharmacology for Canadian Health Care Practice 4th Edition Sealock |9780323694803 | Chapter 1-58 | All Chapters with Answers and Rationals$17.99
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Test Bank For Lilley's Pharmacology for Canadian Health Care Practice 4th Edition By Kara Sealock
Lilley's Pharmacology for Canadian Health Care Practice 4th Edition Test Bank by Kara Sealock
TEST BANK LILLEY'S PHARMACOLOGY FOR CANADIAN HEALTH CARE PRACTICE KARA SEALOCK
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Test Bank for Lilleys Pharmacology for Canadian Health Care
Practice 4th Edition Sealock |9780323694803 | Chapter 1-58 |
All Chapters with Answers and Rationals
When is drug transfer to the fetus most likely to occur? - ANSWER: Last trimester
When is the fetus more susceptible to developing birth defects due to drugs or chemicals the mother
is exposed to? - ANSWER: First trimester
During the spectrum of life, when is there an increased risk of adverse affects to toxicity? - ANSWER:
At both ends of the spectrum; the very young and the very old
True or False: Breast fed infants are at risk for exposure to drugs consumed by the mother - ANSWER:
True
What is the general gastric pH for ages 1-12 - ANSWER: less acidic
in neonatal and pediatrics, how is their gastric emptying compared to adults? - ANSWER: slowed
in neonatal and pediatrics, how is their first-pass elimination compared to adults? - ANSWER: first-
pass elimination reduced
in neonatal and pediatrics, how is their IM absorption compared to adults? - ANSWER: Faster and
irregular
Fill the blanks: in neonatal and pediatrics, ___________________ bile salt formation
___________________ bioavailability. - ANSWER: reduced, decreases
Do neonates and pediatric patients have a higher or lower TBW? - ANSWER: Higher
What does total body water in neonates and pediatrics result in when given a water soluble drug? -
ANSWER: Increased distribution and dilution
in neonatal and pediatrics, what is the level of protein binding compared to an adult? - ANSWER:
Decreased
Immature blood-brain barrier means... - ANSWER: More drugs enter the brain
in the immature liver, what does it not produce enough of? - ANSWER: Microsomal enzymes
(cytochrome P450; P450 enzymes)
Older children may have increased metabolism, what would they require with drug administration but
not with infants? - ANSWER: Higher doses or more frequent administration
With an immature liver, what is an infant at risk of when given drugs? - ANSWER: Pediatric drug
toxicity
Fill the blanks: Kidney immaturity affects _________________ and ____________________. -
ANSWER: glomerular filtration rate, tubular secretion
Decreased perfusion rate of the kidneys may... - ANSWER: reduce excretion of drugs
Factors affecting pediatric drug dosage - ANSWER: -Skin is thin and permeable
-Stomach lacks acid to kill bacteria
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