WGU D027 OBJECTIVE ASSESMENT EXAM LATEST 2024-2025
COMPLETE 400 QUESTIONS AND CORRECT DETAILED VERIFIED
ANSWERS ALREADY GRADED A+
What is the difference in MOA between cholinesterase inhibitors and memantine (namenda)? -
ANSWER-- Cholinesterase inhibitors prevent the breakdown of acetylcholine, whereas
memantine (namenda) regulates the activity of glutamate
What is ataxia? - ANSWER-- Also known as cerebellum attacks
- Degenerative disease of the nervous system
- Many symptoms mimic those of being drunk (i.e. slurred speech, stumbling, falling, and
incoordination)
What causes the symptoms of ataxia? - ANSWER-- The damage caused to the cerebellum, the
part of the brain that is responsible for coordinating movements
- Can also be caused by damage to part of the spinal cord and nerves
What is the treatment for ataxia? - ANSWER-- No treatment
- In some cases, treating the underlying causes (i.e. stopping medications that cause ataxia)
- In other cases, it is a result from chicken pox or other viral infections (likely to resolve on its
own)
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- Genetic causes/predisposed disposition is usually chronic
What causes ataxia in the pediatric population? - ANSWER-- Genetic predisposition
What is Fragile X syndrome (FXS)? - ANSWER-- A genetic condition inherited from parents which
results in various developmental problems
- Rare, but may be dangerous or life-threatening
- Present at birth and is a lifelong condition
- Rarely requires lab testing or imaging
- Often linked to autism (1/3 do have autism)
- X-linked disorder
Since Fragile X Syndrome (FXS) is an X-linked disorder, does a specific gender have a greater
risk? - ANSWER-- Often, females are carriers and males are affected
- However, both males and females can be carriers, and both can be affected by the condition
- Usually milder in females
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How did Fragile X Syndrome (FXS) get its name? - ANSWER-- The gene Fragile X (the FMR1
gene) is on the X syndrome
- Mutation of the FMR1 gene
What is the difference between Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS) and
Fragile X Syndrome (FXS)? - ANSWER-- Both caused by mutations on the FMR1 gene, but they
are caused by different changes in this gene
- FXS is caused by a full mutation
- FXTAS is a premutation
- FXS is present at birth, but display these features in early life
- FXTAS develops in adulthood (usually after age 50) and the symptoms may appear slowly and
develop over the years
- FXTAS individuals are usually healthy with normal cognitive skills prior to the onset
How is Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS) diagnosed? - ANSWER-- Being a
FMR1 premutation carrier
- The appearance of neurological features such as ataxia (balance problems), tremors, and
other symptoms
- MRI findings (changes in the brain)
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What is Prader-Willie Syndrome? - ANSWER-- Genetic disorder that affects many parts of the
body and their growth
- Causes mental and behavioral problems
- Can be dangerous or life threatening if untreated
- Combination of contraceptives contraindicated in breast feeding
- More common in females
- Confirmed from laboratory findings
What is the cause of Prader-Willi Syndrome? - ANSWER-- Depletion of chromosome 15 from
father
- Missing or non-working genes on chromosome 15 (15q11-q13)
- Most cases are not inherited and occur randomly
- Depletion of genes (genes from the region are missing)
- Uniparental disomy - both chromosomes are inherited from the mother
- Imprinting mutation - genes on the paternal chromosome is inactive
What does Prader-Willi Syndrome do to the body? - ANSWER-- Caused the hypothalamus to
malfunction (the area of the brain that affects hunger, thirst, sex and growth hormones)
- In infancy, an individual does not meet development milestones suck as sitting up and walking
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