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NR 565 - ADVANCED PHARMACOLOGY MIDTERM - CHAMBERLAIN UNI NEWLY UPDATED EXAM 2024 |QUESTIONS AND ANSWERS $13.99   Add to cart
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NR 565 - ADVANCED PHARMACOLOGY MIDTERM - CHAMBERLAIN UNI NEWLY UPDATED EXAM 2024 |QUESTIONS AND ANSWERS
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NR 565 - ADVANCED PHARMACOLOGY MIDTERM - CHAMBERLAIN UNI NEWLY UPDATED EXAM 2024 |QUESTIONS AND ANSWERS

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  • August 21, 2024
  • 54
  • 2024/2025
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NR 565 - ADVANCED PHARMACOLOGY
MIDTERM - CHAMBERLAIN UNI NEWLY
UPDATED EXAM 2024 |QUESTIONS AND
ANSWERS



During what trimester is a pregnant woman most at risk for
V V V V V V V V V V



adverse drug reactions with potential long term
V V V V V V V



consequences?
V ANS: 1st trimester (fetus most at VVVVVVVVVV VVV V V V V



risk d/t rapid growth)
V V V V




What is BEERS criteria?
V V ANS: Recommendations V VVVVVVVVVV VVV



of medications inappropriate for elderly (65 and older),
V V V V V V V V



prescriber ultimately decides
V V V




What is the CYP450 (cytochrome P450)
V V V ANS: liver V V VVVVVVVVVV VVV



enzyme system where medications are metabolized, can
V V V V V V V



either be inducers or inhibitors and create drug-drug
V V V V V V V V



interactions
V




CYP450 inducers ANS: Speed up metabolism of
V VVVVVVVVVV VVV V V V



drugs (drug is cleared faster), drug has lesser effect
V V V V V V V V V



(decrease blood levels of drug), elevate CYP450 enzymes
V V V V V V V V

,CYP450 inducers pneumonic
V V VVVVVVVVVV ANS: "Bullshit Crap VVV V



GPS INDUCES rage"
V V V




CYP450 inducer drug names
V ANS: Barbituates, St
V V VVVVVVVVVV VVV V



John wort, Carbamazepine, rifampin, alcohol, phenytoin,
V V V V V V



griseofulvin, phenobarbital, sulfonylureas
V V V




CYP450 inhibitors
V ANS: inhibit metabolism, VVVVVVVVVV VVV V



increase blood levels of medications
V V V V V




CYP450 pneumonic
V ANS: "VISA credit card debt VVVVVVVVVV VVV V V V



INHIBITS spending on designers like CK to look GQ"
V V V V V V V V V




CYP450 inhibitors drug names
V ANS: Valproate,
V V VVVVVVVVVV VVV



isoniazid, sulfonamides, amiodarone, chloramphenicol,
V V V V



ketoconazole, grapefruit juice, quinidine
V V V V




Physiological changes during pregnancy that impact
V V V V V



pharmacodynamics and pharmacokinetic properties of
V V V V V



drugs?
V ANS: increase glomerular filtration rate
VVVVVVVVVV VVV V V V



leads to increase durg excretion
V V V V V V




increase hepatic metabolism
V V




decrease tone and motility of bowel
V V V V V




increase drug absorption
V V

,Examples of medications that can be teratogenic
V V V V V V VVVVVVVVV



ANS: Antiepileptic drugs, antimicrobials such as
V VVV V V V V



tetracyclines and fluoroquinolones, vitamin A in large
V V V V V V V



doses, some anticoagulants, and hormonal medications
V V V V V V



such as diethylstilbestrol (DES).
V V V V




How is absorption of intramuscular medications different
V V V V V V



in neonates?
V V ANS: slow and erratic due to low VVVVVVVVVV VVV V V V V V



blood flow in muscles first few days of life
V V V V V V V V V




Why is absorption of medication in the stomach increased
V V V V V V V V



in infancy?
V V ANS: delayed gastric emptying
VVVVVVVVVV VVV V V




Some medications that should be avoided in the pediatric
V V V V V V V V



patient?
V ANS: glucocorticoids, discoloration of
VVVVVVVVVV VVV V V



developing teeth with tetracyclines, and kernicterus with
V V V V V V V



sulfonamides, levofloxacin (antibiotics)
V V V V




aspirin (Severe intoxication from acute overdose)
V V V V V




what should be included in medication administration
V V V V V V



patient education?
V ANS: dosage size and timing
V VVVVVVVVVV VVV V V V




route and technique of administration
V V V V




duration of treatment V V




drug storage
V

, nature and time course of desired responses
V V V V V V




nature and time course of adverse responses
V V V V V V




finish taking antibiotic
V V




What are some things that put the elderly patient at higher
V V V V V V V V V V



risk for adverse drug reactions?
V V V ANS: reduced renal V V VVVVVVVVVV VVV V



function
V V




polypharmacy (the use of five or more medications daily) V V V V V V V V




greater severity of illness
V V V




presence of comorbidities V V




use of drugs that have a low therapeutic index (e.g.,
V V V V V V V V V



digoxin)
V




increased individual variation secondary to altered
V V V V V



Vpharmacokinetics
inadequate supervision of long-term therapy
V V V V




poor patient adherence
V V




How can healthcare providers decrease likelihood of an
V V V V V V V



elderly patient experiencing an adverse drug reaction?
V V V V V V V VVVVVVV



ANS: obtaining a thorough drug history that includes
VVV VVV V V V V V V



over-the-counter medications
V V




considering pharmacokinetic and pharmacodynamics
V V V



changes due to age
V V V V

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