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Nuclear Medicine Endocrinology Questions and Answers

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Nuclear Medicine Endocrinology Questions and Answers Radionuclide type and doses used for thyroid imaging Tech 5-10 mCi injected - imaged 20 min later with pinhole I- uCi pill (IF uptake only: 100 uCi)- Images 6 and 24 hrs later with pinhole. 20% window at 159keV. I-131 3-4 mCi (IF uptake only:...

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  • August 21, 2024
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  • 2024/2025
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Nuclear Medicine Endocrinology
Questions and Answers
Radionuclide type and doses used for thyroid imaging - answer Tech 5-10 mCi
injected - imaged 20 min later with pinhole
I-123 200-400 uCi pill (IF uptake only: 100 uCi)- Images 6 and 24 hrs later with pinhole.
20% window at 159keV.
I-131 3-4 mCi (IF uptake only: 10 uCi) 20% window at 364keV

What is needed for uptake prior to administering I- and after pt. returns -
answer Prior administration: Count and record dose with probe at 20 cm neck
phantom.
After administration: count background
At 6 hr: count and record with probe at pt's neck and back ground at pt's leg

How to calculate uptake % and what is normal - answer (pt thyroid cnts - pt bkg cnts)
/ (Standard cts - room bkg) x 100
Normal at 6 hrs: 6 to 18 %
Normal at 24 hrs: 10 to 30 %

Primary Causes of Hypotyroidism (diseases) - answer Iodine deficiency (most
common) goiter is common due to high circulating TSH constantly stimulating the gland
Hashimoto (Autoimmune chronic, most common in USA) goiter is the mail clinical
feature
Over treatment with I-131 or meds
Surgical removed

Hashimoto thyroiditis is also called - answer chronic lymphocytic thyroiditis
autoimmune thyroiditis

Grave's Disease - answer a hyperthyroid autoimmune disease where the thyroid
produces w/o the stimulation of TSH

Right Thyroid Nodule - answer

Toxic Thyroid Nodule - answer

Toxic Multinodular Goiter - answer

I-123 and I-131 - answer Radiopharmaceuticals used for Thyroid imaging

I-123 - answer Radiopharmaceutical for thyroid which has photon energy excellent
for imaging

, I-131 - answer Radiopharmaceutical for thyroid which has photon energy excellent
for treatment

Grave's disease - answer Homogeneous, diffusely increased uptake of iodine by
thyroid

Toxic nodule/Multinodular goiter - answer Heterogeneous uptake of iodine by thyroid
with hot nodules

Thyroiditis - answer Depressed uptake of iodine by thyroid

Hormones are _______________ or ______________ - answer proteins or lipids

what do horomones do - answer increase or decrease the rate of cellular activity

Which are the endocrine glands - answer hypothalamus, pituitary (master gland),
thyroid, adrenals, ovaries and testes

hormones released by the hypothalamus are ______ (8) - answer TRH, GnRH, PIH,
GHRH/IH, CRH, MSH/IH

Hormone of Major concern to us - answer Thyrotropin Releasing Hormone

what do the hormones released by the hypothalamus do and what kind of hormones are
these - answer they are petites and control the released of the anterior pituitary

another name for anterior pituitary - answer adenohypophysis

how many hormones are secreted by the anterior pituitary, what type are they and
which one is the main one - answer 7 polypeptide - TSH (thyroid stimulating
hormone)

What does TSH trigger? - answer it triggers the thyroid gland to uptake Iodine for the
production of T3 and T4 (thyroxine)

method for Iodine uptake - answer active trasnport

TSH causes what on the secretory cells of the thyroid - answer mitosis, increasing
size and weight of the gland

how is TSH regulated ? - answer by negative feed back. TSH is inhibited by the
circulating levels T4

Hyperthyroid >> _________________ TSH
Hypo>> _____________ TSH - answer low

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