What labs/assessments should be monitored for patients taking hydralazine and why? - CBC &
antinuclear antibody titer = due to risk of SLE
Peripheral neuritis= due to antipyridoxine effects (B vitamin)
Hydralazine classification - Direct acting vasodilator
Hydralazine pharmacotherpeutics - Adjunct anti-HTN; via IV for severe HTN
How does hydralazine decrease BP? - By disrupting the calcium metabolism of the peripheral vessels and
therefore decreasing PVR
What other therapies are commonly prescribed with hydralazine to counteract its SNS and pro-renin
effects? - Beta blockers/clonidine and anti diuretics
Contraindications for hydralazine? - CAD, mitral valvar rheumatic disease
Adverse effects of hydralazine (mostly due to increased CO) - Palpitations, tachycardia, angina, anorexia,
nausea/vomiting
What is a Serious adverse effect of hydralazine? - SLE
Hydralazine is pregnancy category ______ - C
What symptoms are associated with the reflux effects of hydralazine? - ^HR/SV/CO
Use precaution when administering hydralazine to the following patients:
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