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Exam (elaborations)

NR507 Midterm Exam-Questions with Correct Answers/ Verified

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Hemolytic anemia - -RBCs destroyed Why? -mitchmached blood types-destroys RBCs -autoimmune hemolytic anemia due to autoantibodies against erythrocytes that the immune system pesrceives as an antigen and then attacks it -allergic reaction to a drug causes drug induced hemolytic anemia (drug ind...

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  • August 22, 2024
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  • 2024/2025
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  • NR507
  • NR507
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MikeHarris
NR507 Midterm Exam-Questions with Correct Answers/ Verified

Hemolytic anemia - ✔✔-RBCs destroyed



Why?

-mitchmached blood types-destroys RBCs

-autoimmune hemolytic anemia due to autoantibodies against erythrocytes that the immune system
pesrceives as an antigen and then attacks it

-allergic reaction to a drug causes drug induced hemolytic anemia (drug induced hemolytic anemia)



Pernicious anemia and Vitamin B12 - ✔✔deficiency lack of intrinsic factor



-fatigue

-dyspnea

-peripheral neuropathy (numbness and tingling)



Risk factors:

-older adults

-H-pylori infection

-affects vitamin B12 absorptions



iron deficiency anemia causes: - ✔✔causes:



-decreased dietary intake

-occult bleeding (hemorrhage, postpartum bleed, colitis, cirrhosis, GI ulcers, esophageal lesions or
menorrhagia



-takes 2-4ml (1tsp) of blood loss a day to lose 1-2 mg of iron



iron deficiency anemia - ✔✔-is microcytic/hypochromic anemia



-caused by disorders of hemoglobin synthesis, particularly iron deficiency

, -ferritin helps to measure body total iron stores

-low ferritin indicates anemia

-increased RBC distribution width is one of the earliest lab markers in developing microcytic or
macrocytic anemia



Microcytic anemia - ✔✔-MCV less than 80

-iron deficiency

-sideroblastic

-thalassemia

-anemia of chronic disease



Normocytic anemia - ✔✔-MCV 80-99

-hereditary spherocytosis

-G6PD deficiency

-paroxysmal nocturnal hemoglobinuria



macrocytic anemia - ✔✔-MCV greater than 100

-B12 deficiency (pernicious anemia)

-folate deficiency



consequences of decreased oxygenation due to lack of hgb - ✔✔-severe fatigue

-pallor

-weakness

-dyspnea

-dizziness



Hematological Diseases - ✔✔-iron deficiency

-pernicious anemia

-hemolytic anemia

-sickle cell anemia

-thalassemia

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