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ASCP MB Exam Practice Questions and Complete Solutions Graded A+ $14.49   Add to cart

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ASCP MB Exam Practice Questions and Complete Solutions Graded A+

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  • ASCP CG
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  • ASCP CG

ASCP MB Exam Practice Questions and Complete Solutions Graded A+

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  • August 22, 2024
  • 30
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • ASCP CG
  • ASCP CG
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ASCP MB Exam
Practice Questions
and Complete
Solutions Graded
A+
Denning [Date] [Course title]

,Mutation in UGT1A1 affects metabolism of what drug?

Irontecan

Phenobarbital

Indinavir

Sorafenib - Answer: Irontecan



Its discovery shed light on why there is simultaneous, though not continuous, synthesis of DNA on both
leading and lagging strands of DNA:

Klenow fragment of DNA polymerase

Okazaki fragments

Sanger fragments

RNA fragments - Answer: Okazaki fragments



What gene is measured following treatment with Warfarin?

FLT3

VKORC1

MAPK

P53 - Answer: VKORC1



What stain binds to minor groove of DNA Duplex?

SYBR1

EtBR

Propidium iodide

Methyl green - Answer: SYBR1



A parent has an autosomal dominant disorder. What percent chance does this parent have to pass down
this affected gene to his/her child?

0%

25%

, 50%

75%

100% - Answer: 50%



The bond between a phosphate group and the ribose sugar group in RNA is called which of the
following?

Phosphodiester linkage

Glycosidic bond

Peptide bond

Amide bond - Answer: Glycosidic bond



Branched DNA amplification (bDNA) is best classified as:

Signal amplification

Target amplification

Probe amplification

None of the above - Answer: Signal amplification



In which of the following methods is the probe digested by the polymerase (Taq) during primer
extension?

Taqman

FRET probes

Molecular beacons

Scorpion probes - Answer: Taqman



A patient with impaired judgment, personality changes, signs of abnormal body movements and
depression comes to the physician's office for a follow-up visit. The physician suspects a single-gene
disorder may be the cause of those clinical manifestations. A blood specimen was then sent to your
clinical laboratory for mutation screening in the Huntingtin gene. Testing with standard PCR indicates
that patient has Huntington Disease, HD. Which of the following would be consistent with this
diagnosis?

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