Find the palindrome in this restriction enzyme site: 5'-CTGCAG-3'?
5'-GAC
3'-GAC
3'-CTG
5'-GTC - Answer: 3'-GAC
A patient with impaired judgment, personality changes, signs of abnormal body movements and
depression comes to the physician's office for a follow-up visit. The physician suspects a single-gene
disorder may be the cause of those clinical manifestations. A blood specimen was then sent to your
clinical laboratory for mutation screening in the Huntington gene. Testing with standard PCR indicates
that patient has Huntington Disease, HD. Which of the following would be consistent with this
diagnosis?
25 CAG repeats in the Huntington gene
85 CAG repeats in the Huntington gene
25 CGA repeats in the Huntington gene
85 CGA repeats in the Huntington gene - Answer: 85 CAG repeats in the Huntington gene
Which two HPV types are responsible for most cases of cervical cancer?
, 16 and 18
31 and 59
16 and 58
44 and 59 - Answer: 16 and 18
Replication forks, known as origins of DNA replication, are created by this enzyme:
Ligase
Taq Polymerase
Primase
Helicase - Answer: Helicase
Mutation in what gene is associated with Fragile X syndrome? - Answer: FMR1
Mantle cell lymphoma (MCL) is caused by what translocation? - Answer: t(11;14)
This polymerase is involved in "initiation of DNA replication and has primase activity": - Answer: Pol α
Its discovery shed light on why there is simultaneous, though not continuous, synthesis of DNA on both
leading and lagging strands of DNA:
Klenow fragment of DNA polymerase
Okazaki fragments
Sanger fragments
RNA fragments - Answer: Okazaki fragments
What gene is measured following treatment with imatinib (Gleevec)?
FLT3
BCR/Abl
Jak2
MAPK - Answer: BCR/Abl
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