Exam (elaborations)
PHM 450 Exam 3 Questions With Complete Solutions
- Course
- PHM 450
- Institution
- Florida State University
PHM 450 Exam 3 Questions With Complete Solutions
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PHM 450 Exam 3 Questions With Complete Solutions4 Types of Acute Response for Toxicant-Induced Lung Injury
Correct Answers 1) Response 1: Bronchitis (acute
inflammatory)
-inflammation of mucus memb. of the bronchi
-irritant->epithelium damage->neutrophil infiltration->mucus
hypersecretions
-symptoms: productive cough, shortness of breath
2) Response 2: Bronchoconstriction (airway hyperreactivity)
-decrease in lumen diameter in bronchi and bronchioles due to
activation of airway smooth muscle
-accompanied by increased airway mucus
3) Response 3: Pulmonary (O)edema
-increased fluid within alveoli
-typically due to pulmonary failure
4) Response 4: Cell Proliferation
-progenitor cells differentiate into "active" cells
-alveolar type II epithelial cells proliferate to replace damaged
alveolar type I cells
-Clara cells in the bronchi differentiate to replace damaged
ciliated epithelial cells
Alveoli
-function
-defense mechanisms Correct Answers -Lower Respiratory
-site of gas exchange* (respiration in lungs)
-***primary functional unit of the resp system
-defense mechanisms: ingest bacteria, secrete over 100
substances, Express IgG and complement receptors on their
surface
, antioxidants Correct Answers prevents against oxidant injury
antiproteases Correct Answers protects against proteases
Bile (structure/function) Correct Answers Structure: yellow
fluid containing many electrolytes, bile acids, phospholipids,
BILIRUBIN, cholesterol, and protein
Function (3):
1. bile provides the sole excretory route for many solutes that are
not excreted by the kidney
2. secreted bile salts and acids are required for normal lipid
digestion and absorption
3. Biles acids- derived from cholesterol, rate determining step
CYP7A1
Bile flow Correct Answers opposite of blood flow!
Bronchi Correct Answers -Respiratory Epithelium
-pseudostratified ciliated
-secretory cells
-cartilage plates
- smooth muscle fibers
-submucosal glands
Chronic Obstructive Pulmonary Disease (COPD)
-what two diseases does it contain?
-What does is feature?
-what is it characterized by? Correct Answers includes two
diseases:
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