NURA 1550- Respiratory Exam Questions and Answers
First gen H1 receptor antagonists (blocker) - Answer-1. Oldest, inexpensive, widely available
What does First gen H1 prevent? - Answer-1. Reduce most physiologic effects
2. Inhibit smooth muscle constriction in blood vessels, respiratory, GI ...
First gen H1 receptor antagonists (blocker) - Answer-1. Oldest, inexpensive, widely
available
What does First gen H1 prevent? - Answer-1. Reduce most physiologic effects
2. Inhibit smooth muscle constriction in blood vessels, respiratory, GI tract
3. Decrease capillary permeability/salivation and tear formation
Diphenhydramine (Benadryl) - Answer-1. Action- black histamine at H1 receptor sites
2. Adverse effects- CNS depression
Other drugs in first gen H1 class? - Answer-Chlorphenkramine, hydroxyzine (vistaril),
promethazine (phenergen)
BBW for promethazine - Answer-Severe chemical and tissue damage when
administered intravenously
Cetirizine (Zyrtec) - Answer-1. Second gen (gained specificity)
Action- competes with histamine for receptor sites
Adverse effects- do not readily enter the brain from the blood, reducing CNS adverse
effects
Other drugs in second gen H1? - Answer-Loratadine (Claritin)
Fexofenadine (Allegra) - Answer-1. Third gen H1 antagonist
2. Action- bind preferentially to peripheral rather than central H1 receptors. Does not
cross blood brain barrier reducing occurrence of adverse drug reactions like drowsiness
and sedation, provides relief
Albuterol action - Answer-Stimulates the Beta 2 adrenergic receptors in the lungs, which
relaxes the bronchial smooth muscle, thus causing bronchodilation.
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