NURS 3366 Mechanisms of Defense & Alterations:
Inflammation, Immune Function (RRD #3) Questions With
Complete Solutions
An example of a congenital cell-mediated (T-cell)
immunodeficiency is: Correct Answers DiGeorge's Syndrome
An example of a congenital combined B and T cell
immunodeficiency is ________________. Correct Answers
Severe combined immunodeficiency syndrome (SCIDS).
An example of a congenital humoral (B-cell) immunodeficiency
is: Correct Answers x-linked hypogammaglobulinemia (IgG is
missing or lessed in amount)
An example of an acquired cell-mediated (T-cell)
immunodeficiency is: Correct Answers HIV (an RNA
retrovirus) and AIDS
Describe two qualitative defects in phagocytes. Correct
Answers 1.) "chemotactic defects" - they won't respond
appropriately when summoned.
2.) impaired function: phagocytes damaged by diabetes mellitus
have decreased ability to fight microbes.
Examples of causes of acquired combined B and T cell
immunodeficiencies would be: Correct Answers radiation and
cytotoxic drugs used to treat cancer
immunosuppresant drugs used post transplant
aging
, Give four examples of abnormal inflammation. Correct
Answers SIRS
sepsis
septic shock
chronic inflammation disorders (there are lots of these)
How do B-cells work? Correct Answers They defend the body
using a more complicated method:
they differentiate into plasma cells
they plasma cells create antibodies to the microbe that has
attacked the body
a particular set of antibodies (memory) now will always
remember and lay in waiting for that specific microbe
How do T-cells work? Correct Answers They defend the body
by direct attack against invading microbes.
How is granulating tissue produced? Correct Answers
Granulating tissue (pink, healthy, healing tissue) is produced by
clotting factors, platelets, and fibrin.
Identify therapeutic actions for inflammation. Correct Answers
1.) protected ice
2.) using antiinflammatory medications (NSAIDS and steroids)
to suppress the effects of prostaglandins.
If bacteria or other microbes have caused irritation / injury to a
cell, what is the role of the macrophage? Correct Answers
Macrophages phagocytize and process them. They will:
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