NURS 2320
Introduction to
Pharmacology
(284 questions
already graded
A+)
Additive effects - answer Drug interactions in
which the effect of a combination of two or more
drugs with similar actions, administered at the
same time, is the action of one plus the action of
the other, with the total effect of both drugs being
given
Adverse drug event (ADE) - answer Any
undesirable occurrence related to administering or
failing to administer a prescribed medication
,Adverse drug reaction (ADR) - answer Any
unexpected, unintended, undesired, or excessive
response to a medication given at therapeutic
doses
Adverse effects - answer A general term for any
undesirable effects that are a direct response to
one or more drugs
Agonists - answer Drugs that bind to and stimulate
the activity of one or more receptors in the body
Allergic reaction - answer An immunological
hypersensitivity reaction resulting from the
unusual sensitivity of a patient to a particular
medication; a type of adverse drug event
Antagonists - answer Drugs that bind to and inhibit
the activity of one or more receptors in the body
Also called inhibitors
Antagonistic effects - answer Drug interactions in
which the effect of a combination of two or more
drugs is less than the sum of the individual effects
of the same drug given alone
Usually caused by an antagonizing (blocking or
reducing) effect of one drug on another
,Bioavailability - answer A measure of the fraction
of drug administered dose that is delivered to the
system circulation (from 1-100%)
Biotransformation - answer One or more chemical
reactions involving a parent drug
Blood brain barrier - answer The barrier system
that restricts the passage of various chemicals and
microscopic entities (e.g. bacteria, viruses)
between the bloodstream and the CNS but allows
for the passage of essential substances such as
oxygen
Chemical name - answer The name that describes
the chemical composition and molecular structure
of a drug
Contraindication - answer Any condition, especially
one related a disease state or patient
characteristic, including current or recent drug
therapy, that renders a particular form of
treatment improper or undesirable
, Cytochrome P450 - answer The general name for a
large class of enzymes that play a significant role
in drug metabolism and drug interactions
Dissolution - answer The process by which solid
forms of drugs disintegrate in the GI tract and
become soluble before they are absorbed into
circulation
Dependence - answer A state in which there is a
compulsive or chronic need for a drug
Drug - answer Any chemical that affects the
physiological processes of a living organism
Drug actions - answer The processes involved in
the interaction between a drug and body cells (e.g.
the action of a drug on a receptor protein)
Also referred to as mechanism of action
Drug effects - answer The physiological reactions
of the body to a drug
Can be therapeutic or toxic and describe how the
body is affected as a whole by the drug
The terms onset, peak, and duration are used to
describe drugs effects (most often referred to as
therapeutic effects
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