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NR601 Midterm Exam | Questions And Answers Latest {} A+ Graded | 100% Verified

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NR601 Midterm Exam | Questions And Answers Latest {} A+ Graded | 100% Verified

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NR601 Midterm Exam | Questions And Answers Latest {2024- 2025} A+ Graded | 100%
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What are the 3 primary physiological changes of aging? - 1. Reduced physiological reserve of most body

systems, esp. cardiac, resp, renal.




2. Reduced homeostatic mechanisms that fail to adjust regulatory systems (i.e. temp control, fluid/lyte

balance, etc.).




3. Impaired immunological function (infection risk is greater, autoimmune dz's more prevalent)




What is the preferred amount of exercise for elderly? - 30min/day 5 days/wk of moderate exercise.




If trying to lose wt: 60min/day.




What are PFTs? - Group of tests that provide quantifiable measurement of lung function, used to dx resp

abnormalities or assess progression/resolution of lung dz.




What is FEV1? - Forced Expiratory Volume in 1 second (80-120%)




What is FVC? - Forced Vital Capacity (80-120%)

,What is normal FEV1/FVC ratio? - <0.7 (70%)




What is GOLD 1 criteria? - Mild


FEV1 >/= 80% predicted




What is GOLD 2 criteria? - Moderate


FEV1 50-79% predicted




What is GOLD 3 criteria? - Severe


FEV1 30-49% predicted




What is GOLD 4 criteria? - Very severe


FEV1 <30% predicted




What are the signal symptoms of COPD? - Dyspnea


Chronic cough w/sputum


Decreased activity tolerance


Wheezing

,What are characteristics of COPD? - Common, preventable, treatable.




Characterized by persistent airflow limitation.




Usually progressive, associated with enhanced chronic inflammatory response in airways and lungs to

noxious particles/gases




Airway fibrosis, luminal plugs, airway inflammation, increased airway resistance, small airway dz.




Decreased elastic recoil of alveoli.




What are risk factors for COPD? - Smoking (increasing w/number of pack years)


Second hand smoke


Environmental pollution (endotoxins, coal dust, mineral dust)




What is seen on phys exam in COPD? - May be normal in early states

, As severity progresses: lung hyperinflation, decreased breath sounds, wheezes at bases, distant heart

tones (b/c of hyperinflation, so S1/S2 sounds off in distance), accessory muscle use, pursed lip breathing,

increased expiratory phase, neck vein distention.




How is COPD diagnosed? - Spirometry is gold standard (pre and post bronchodilator).


Irreversible airflow limitation is hallmark.




How is COPD treated? - Bronchodilators: beta agonists (long/short), anticholinergics (long/short), or

combo.




What is the MOA of beta agonists? - Stimulates beta-2-adrenergic receptors, increasing cyclic AMP,

resulting in relaxing airways.




What is the MOA of anticholinergics? - Block the effect of acetylcholine on muscarinic type 3 receptors,

resulting in bronchodilation.




Why are long-acting beta agonists prescribed for COPD? - They are for moderate airflow limitation.




They relieve symptoms, increase exercise tolerance, reduce number of exacerbations, improve QOL.

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