Final Exam: NR568 / NR 568 (Latest
Update ) Advanced
Pharmacology for the Adult-
Gerontology Primary Care Nurse
Practitioner
| Exam Guide Review | 100%
Correct | Grade A - Chamberlain
Question:
Which of the following describes the mechanisms of action of antiseizure
medications? Select all that apply.
Answer:
The mechanisms of action of antiseizure medications include suppression of
sodium influx, suppression of calcium influx, promotion of potassium efflux,
blockade of glutamate receptors, and an increase of gamma-aminobutyric
acid (GABA). Antiseizure drugs are known to suppress the discharge of
neurons within a seizure focus and suppress the propagation of seizure
activity to other areas of the brain. Recently, it was discovered that nearly all
antiseizure drugs act through five basic mechanisms: suppression of sodium
influx, suppression of calcium influx, promotion of potassium efflux,
blockade of receptors for glutamate, and potentiation or increase of gamma-
aminobutyric acid (GABA).
,Question:
Chlamydia
Answer:
doxycycline - taken every day for a week.
azithromycin - one dose of 1g, followed by 500mg once a day for 2 days.
Question:
Uncomplicated gonococcal urethritis
Answer:
For treatment of NGU, the CDC currently recommends doxycycline, 100 mg
orally twice a day for 7 days. Alternative regimens include a single dose of 1 g
azithromycin orally, or 500 mg orally followed by 250 mg orally daily for 4 day
Question:
Bacterial Vaginosis
Answer:
Metronidazole — Metronidazole, taken over multiple days, is one of the most
effective treatments for BV. Metronidazole is available as an oral pill or vaginal
gel; the choice of pill or gel is based on the person's preferences. The oral pill
is taken twice daily for seven days.
,Question:
Herpes Simplex Virus
Answer:
Acyclovir 400 mg orally 3 times/day for 5-10 days. OR.
Famciclovir 500 mg orally 2 times/day for 5-10 days. OR.
Valacyclovir 1 gm orally 2 times/day for 5-10 days
During an outbreak, you may use an antiviral ointment or cream to help
lessen your symptoms and help them go away faster, but it only works if you
start it soon after you start an outbreak. Many people with HSV-2 take daily
oral medications to keep outbreaks at bay.
Your provider may prescribe a topical (applied to the skin) medication or oral
medication such as:
Acyclovir (Sitavig®, Zovirax®).
Famciclovir (Famvir®).
Valacyclovir (Valtrex®).
Question:
• Trichomoniasis
Answer:
Trichomoniasis is usually treated quickly and easily with antibiotics. Most
people are prescribed an antibiotic called metronidazole, which is very
effective if taken correctly. You'll usually have to take metronidazole twice a
day, for 5 to 7 days. Sometimes this antibiotic can be prescribed in a single,
larger dose.
, Question:
Syphilis
Answer:
The recommended treatment for primary, secondary or early-stage latent
syphilis is a single shot of penicillin. If you've had syphilis for longer than a
year, you may need additional doses. Penicillin is the only recommended
treatment for pregnant people with syphilis.
Question:
Amaya is Asian. When considering a change in antiseizure medications,
which of the following medications carry a higher risk for Amaya?
Answer:
Carbamazepine and phenytoin both carry a higher risk for Steven Johnson's
Syndrome (SJS) or toxic epidermal necrolysis (TEN) for Asians. Product
labeling warns that the risk for developing SJS or TEN is strongly associated
with a genetic mutation known as human leukocyte antigen (HLA)-B*1502,
which occurs almost exclusively in people of Asian descent. For this reason,
phenytoin should not be prescribed for patients known to have this mutation
Question:
SSRI baseline data
Selective Serotonin Reuptake Inhibitors
Answer: