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Veterinary Pharmacology Final Exam.
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Veterinary Pharmacology Final Exam.
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Veterinary Pharmacology Final ExamPhospholipase j- jANS-Phospholipids jare jmade jinto jarachidonic jacid jby jwhat
jenzymes?
Cyclooxygenase j- jANS-Arachidonic jacid jis jmade jinto jPGG2 jby jwhat jenzyme?
Anti-inflammatory, janalgesic jand jantipyretic j- jANS-What jare jthe j3 jpharmacological
jeffects jof jNSAIDs?
Anti-inflammatory j- jANS-What jpharmacological jeffects jof jNSAIDs?
- jmodifications jof jinflammatory jreactions
- jdecrease jin jinflammatory jprostaglandin jproduction
Analgesic j- jANS-What jpharmacological jeffects jof jNSAIDs?
- jreduction jof jpain
Antipyretic j- jANS-What jpharmacological jeffects jof jNSAIDs?
- jlowering jof jraised jtemperature
- jpartly jdue jto jdecreased jrelease jof jprostaglandins jin jresponse jto jinterleukin-1 j(IL-1)
TXA2 j- jANS-The jantithrombotic jeffect jis ja jside jeffect jof jNSAIDs jbecause jthey jinhibit
j____ jsynthesis
False j(causes jstomach julcers jand jinternal jbleeding) j- jANS-True/False
Concurrent juse jof jcorticosteroids jand jNSAIDs jshould jbe javoided jdue jto jincreased
jrisk jof jrenal jfailure?
COX2 j- jANS-Which jCOX jis jthe jinducible jform? jAlso jit jsynthesizes jprostaglandins
jresponsible jfor jinflammation jand jpain
COX1 j- jANS-Which jCOX jis jthe jbasal jform? jAlso jit jsynthesizes jprostaglandins jfor
jmaintenance jand jprotection jof jthe jGI jtract
Aspirin j- jANS-____ janti-inflammatory jMechanism, jpermanently jinactivates
jprostaglandin jsynthase juntil jit jis jreplaced jby jnew jsynthesis, jgranulocytes j(neutrophils,
jeosinophils, jmast jcells, jand jbasophils) jalso jeffected
Rimadyl j(Carprofen) j- jANS-- jWorld's jmost jfrequently jprescribed jcanine jNSAID
- jIndicated jfor jthe jrelief jof jpain jand jinflammation jassociated jwith josteoarthritis jin jdogs
- jReceived japproval jfor jcontrolling jpost joperative jpain jassociated jwith jsoft jtissue jand
jorthopedic jsurgery jin jdogs
, - jLower jincidence jof jGI jdisturbance
False j(NEVER) j- jANS-True/False
You jcan jsometimes jadminister jcats jCarprofen j(Rimadyl) jfor jOA
injectable j- jANS-The j____ jform jof jRimadyl jis jindicated jfor jthe jcontrol jof jpain jand
jinflammation jassociated jwith josteoarthritis jand jboth jsoft jtissue jand jorthopedic
jsurgeries
phenobarbital j- jANS-Concurrent juse jof jcarprofen jand j____ jcan jalter jthe jactivity jof
jone jor jboth jdrugs
Zubrin j(Tepoxalin) j- jANS-___ jmechanism jof jaction jis jinhibition jof jcyclooxygenase
jactivity jand jlipoxygenase jand jis jthus jclassified jas ja jdual jinhibitor jof jarachidonic jacid
jmetabolism
True j- jANS-True/False
Zubrin jis jnot japproved jin jcats
leukotrienes j- jANS-By jusing jZubrin jin jdogs jyou jare jinhibiting jlipoxygenase jwhich jis
jused jto jproduced jinflammatory j_____
Previcox j(firocoxib) j- jANS-- jApproved jto jtreat jpain jand jinflammation jin jdogs jsuffering
jfrom josteoarthritis jand jreported jto jhave j24-hour jtherapeutic jpain jrelief
- jselectively jinhibit jCOX-2 jcyclooxygenase jactivity
False j- jANS-True/False
Previcox jis jindicated jfor juse jin jcats
Anorexia j- jANS-What jis jthe jcommon jinitial jsign jin janimals jwho jhave ja jrisk jof
jhepatotoxicity jwhen jon jan jNSAID
ALT j- jANS-3-4 jfold jincreases jin j___ j(a jlab jtest) jabove jnormal jrange jmay jbe jan
jindication jof jacute jhepatopathy jwhen ja jdog jis jon jan jNSAID
Cosequin j(glucosamine jand jchondroitin jsulfate) j- jANS-is jmarketed jas ja jveterinary
jnutraceutical, jand jclaims jto jstimulate jthe jsynthesis jof jsynovial jfluid jand jinhibits
jdegradation jof jthe jarticular jcartilage
Adequan j- jANS-- jis jan jFDA-approved jglycosaminoglycan jpolysulfate jester jand jis
jcommonly jcalled jP-GAGS
- jone jclinical jstudy jof jdogs jwith jhip jdysplasia jfound jgreatest jimprovement jin
jorthopedic jscores jat jdosages jof j4.4 jmg/kg, jIM jevery j3-5 jdays jfor j8 jinjections
broad j- jANS-____ jspectrum jantibacterials jare jactive jagainst jboth jGram-positive jand
jGram-negative jorganisms. j
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