Exam (elaborations)
Advanced Pathophysiology (Nurse 580) LATEST EXAM 2024/2025
- Course
- Advanced Pathophysiology
- Institution
- Walden University
Advanced Pathophysiology (Nurse 580) LATEST EXAM 2024/2025
[Show more]
Content preview
Advanced Pathophysiology (Nurse580) LATEST EXAM 2024/2025
Abnormalities of chromosomal structure - ANSWER -Deletions: chromosomal breakage or
loss of DNA
-Duplications: Excess genetic material; usually results in less serious consequences
-Inversion: chromosomal rearrangement in which chromosome segment is inverted. Usually affects
offspring
-Translocation: is the interchange of genetic material between non-homologous chromosomes ;
common in Downs Syndrome
-Reciprocal: breaks take place in two different chromosomes and material is exchanged
Activation of Mast Cells (causes/release pathways) - ANSWER -physical injury
-chemical agents
-immunologic processes
-toll-like receptors
*chemicals release in 2 ways: 1) degranulation (histamine)
2) synthesis of lipid derived chemical mediators
Alzheimer Disease (AD) - ANSWER Multifactorial Disorder
-familial history w/in 1st generation doubles risk
-affects amyloid-beta disposition
-precursor protein (APP gene) is the primary cause of AD
Aneuploidy - ANSWER Abnormal number of chromosomes.
-caused by nondisjunction
Aneuploidy of sex chromosomes - ANSWER
autosomal aneuploidy - ANSWER -Down syndrome (Trisomy 21)
, Advanced Pathophysiology (Nurse
580) LATEST EXAM 2024/2025
-1/800 births
-dependent on age
-increased risk of congenital heart disease, resp. infections, and leukemia
Autosomal recessive inheritance - ANSWER -rare
-many individuals are carriers
-abnormal allele is recessive
-condition is expressed equally in males and females
-consanguinity increased chance of autosomal recessive inheritance
recurrent risks: 25%
Barr bodies - ANSWER inactivated X chromosomes found only in females (always 1 less
than the number of the X chromosomes in the cell)
Cellular mediators of Inflammation - name the cellular components - ANSWER -
Erythrocytes
-Platelets
-Leukocytes
*cellular receptors
*cellular products = cytokines
CHD - ANSWER Multifactorial Disorder
coronary heart disease; potential MI caused by atherosclerosis
Chemokines - ANSWER -attract leukocytes to site of inflammation
-synthesized by many cells (macrophages, fibroblasts, endothelial cells)
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller mikedoc. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $27.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
78075 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now