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NR507 hematologic disorders questions with answers
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NR507 hematologic disorders questions with answers
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NR507 hematologic disorders questionswith answers
the site of blood cell formation hematopoiesis varies with age - .......🔷ANSWERS🔶......✔✔ -fetus -
yolk sac beginning 3rd week gestation; shift to fetal liver & spleen by week 8 and to bone marrow by
5 month
-birth to 5 years red marrow of all bones make blood cells
-after 20 years red marrow primarily located in ilium, vertebrae, cranium and jaw, sternum and ribs,
humerous and femur.
Hematopoiesis occurs throughout life and is stimulated by - .......🔷ANSWERS🔶......✔✔ infiltration
of the yellow or fatty bone marrow with red bone marrow cells.
faster proliferation and differentiation of stem and daughter cells.
Hematopoietic stem cells are - .......🔷ANSWERS🔶......✔✔ -are progenitors (apart of) of all
hematological cells.
-proliferate and differentiate under the control of numerous growth factors and cytokinis to form the
three types of cells found in peripheral blood: RBCs, WBCs, and platelets
Erythropoiesis - .......🔷ANSWERS🔶......✔✔ formation of red blood cells:
-The growth factor erythropoietin is made by the kidney and to a very small extent in the liver in
response to tissue hypoxia
-is also stimulated by androgens (testosterones)
, -Normal red blood cell level is between 4.2 to 6.2 million cells per cubic millimeter (approximately
45% of blood volume)
-able to replenish 1% of circulating red blood cell mass every 24 hours, which is equivalent to 2.5
million red blood cell synthesized per second.
The mature RBC structure - .......🔷ANSWERS🔶......✔✔ biconcave spherical disk for maximum
surface area for gas exchange
reversible deformability to squeeze through capillaries
lacks a nucleus, ribosome, mitochondria ( Without these structures, red blood cells cannot divide or
do protein synthesis and can only perform anaerobic metabolism,
lifespan in circulation is approximately 100-120 days (But in that time frame, it will have traveled
thousands of miles to our vascular system)
Red blood cells are essentially a sack of hemoglobin. - .......🔷ANSWERS🔶......✔✔ It is estimated
that there are approximately 300 million hemoglobin molecules per red blood cell. Hemoglobin
makes up 90% of the dry weight of the cell.
males 16
females 14
Hemoglobin has a unique chemical composition that includes polypeptide chains, heme molecules,
and iron.
iron - .......🔷ANSWERS🔶......✔✔ -The primary dietary sources for iron are meats, especially red
meat, dry beans, and eggs.
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