PHARMACOLOGY - FNP EXAM QUESTIONS AND
ANSWERS
Macrolides (erythro, clarithro, pediazole), Antifungals (ketoconazole, fluconazole),
Cisapride (Propulsid) *Been pulled, Cimetidine (Tagament), Citalopram (Celexa) -
Answers -Causes the most interactions
Cause or exacerbate CHF in some patient. Do not use in Class III or IV heart failure;
Stop Actos if c/o dyspnea, weight gain, cough (heart failure) - Answers -
Thiazolidinediones (TZDs) - Pioglitazone (Actos)
High risk of weight gain, metabolic syndrome, and type 2;
Monitor weight every 3 months, higher mortality in elderly patients
Monitor TSH, lipids, weight/BMI - Answers -Atypical antipsychotics -
Risperidone (Risperdal)
Olanzapine (Zyprexa)
Quietipine (Seroquel)
Serum potassium (baseline, during, dose change, illness)
Do not mix with ACEI/ARBS - high risk for hyperkalemia
Avoid with severe renal disease - high risk for hyperkalemia - Answers -While on
Potassium-Sparing Diuretics monitor
Edema from heart failure
cirrhosis
renal disease
HTN
*More potent than thiazides, but with shorter duration of action - Answers -Loop
Diuretics -
Furosemide (Lasix)
Bumetanide (Bumex)
Low levels of chlorine
Hypokalemia
Hyponatremia
Hypovolemia
Hypotension
Ototoxicity (Do not combine with aminoglycosides)
Pancreatitis
Jaundice
Rash - Answers -Loop Diuretics adverse effects
Galactorrhea
Hyperkalemia
, high risk for certain cancers and rarely used to treat HTN
Risk for benign and malignant tumors - Answers -Aldosterone Antagonists - adverse
effects
Spironolactone (Aldactone)
Uses:
Migraine prophylaxis
HTN
First line for post-myocardial infarction
Angina
Arrhythmias
Bronchospasm
Bradycardia
Depression, fatigue (be careful with elderly)
ED
Blunts hypoglycemic response
Do not use in anyone with asthma or airway problems and do not give to pt. with
bradycardia or 2nd and 3rd degree heart block (AV block)
Do not discontinue abruptly d/t severe rebound hypertension - Answers -Beta Blockers
adverse effects
First line for HTN in diabetics
First line for pt with CKD (proteinuric)
Diabetes (renal)
CKD
MOA -Blocks conversion of angiotensin I to angiotensin II (potent vasoconstrictor) -
Answers -ACEI - ending in "pril"
Angioedema and anaphylactoid reactions
ACEI cough (occurs within first few months, stop ACE and switch to ARB)
Hyperkalemia - Answers -ACEI and ARBs adverse effects
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