Medical Biotechnology Questions with Verified Answers 2025
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Course
Medical Biotechnology
Institution
Medical Biotechnology
Medical Biotechnology Questions with Verified Answers 2025
Medical Biotechnology - correct answer -The discipline of improving human health through advancements of disease prevention, diagnosis, and treatment.
Leeches - correct answer -Small worm that withdraws small amounts of blood. Enzymes i...
Medical Biotechnology Questions with Verified
Answers 2025
Medical Biotechnology - correct answer -The discipline of improving human
health through advancements of disease prevention, diagnosis, and
treatment.
Leeches - correct answer -Small worm that withdraws small amounts of
blood. Enzymes in the saliva can have the potential to dissolve blood clots.
Homologue - correct answer -A related gene in a different species. Such
relation can be used for treatments by using the organism as a model
organism to determine how certain drugs/treatments would affect humans.
Model Organism - correct answer -Nonhuman organisms that scientists use
to study biological processes in a lab environment. They can be used to
identify diseased genes, test therapies, and safety. Ie: Mice, fruit flies,
worms.
Leptin - correct answer -Protein that regulates hunger. Created by the ob
gene. Mice become obese if the gene is missing.
C. elegans - correct answer -Finite number of cells (959). 131 cells care
destined to die via apoptosis when cells are old. Can be used to determine
the age of the worm and determine what factors can speed up aging.
Creation of Heart Attack Mice - correct answer -1. Knock out of genes that
metabolize cholesterol.
2. Mice have high blood cholesterol, leading to atherosclerosis.
3. Mice very prone to heart attach.
4. Test therapies are done to treating cardiovascular disease.
Atherosclerosis - correct answer -Hardening of arteries.
, Difficulty of Drugs for AIDS - correct answer -High priority. Difficult to
obtain model organisms since no other organism can have AIDS, except
monkeys, which are expensive. Rodents may one day be infected with HIV.
FDA - correct answer -Food an dDrug Administration
Oversees food, drug, and devices
Monitors clinical trials
Approves drugs
Preclinical Testing - correct answer -Identification of lead compound.
Evaluate safety and efficacy.
In vitro studies (interaction of drug to target)
Model organism testing
Chemistry tests (purity, shelf life, stability)
Development studies (dosing, packaging, administration)
Lasts 6-7 years.
Pharmackinetics - correct answer -Study of: absorption, distribution,
metabolism, and excretion in an organism.
IND - correct answer -Investigational New Drug Application. Filed after
preclinical testing to begin human testing.
NDA - correct answer -New Drug Application. Filed after Phase III clinical
trials to prove trials were safe and effective and more effective than
placebo. Filed to drug and go on market.
Clinical Trials - correct answer -Process of testing products prior to
marketing and provide treatment plan for use in humans.
Informed Consent - correct answer -Participants in clinical trials must
understand the risks and benefits of drugs by signing a document so the
company does not get sued if something goes askew during test.
Phase I - correct answer -20-80 healthy volunteers tested for
pharmacokinetics of drug and a safe dose range. Takes 6 months-1 year to
complete.
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