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MICR 2123: Final Exam Questions With Complete Solutions

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MICR 2123: Final Exam Questions With Complete Solutions 5 levels of intracellular control of gene expression - 1. DNA 2. transcription 3. post-transcription 4. translation 5. post-translation /.ABC transport - energy comes from ATP hydrolysis /.ability needed by nose and mouth micro...

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  • August 28, 2024
  • 17
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • MICR 2123:
  • MICR 2123:
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5 levels of intracellular control of gene expression - 1. DNA
2. transcription
3. post-transcription
4. translation
5. post-translation

/.ABC transport - energy comes from ATP hydrolysis

/.ability needed by nose and mouth microbiota - All colonizers here need to be able to
adhere to surfaces to avoid flushing to the acidic stomach

/.accidental transmission - when a host that is not part of the normal infection cycle
unintentionally encounters that cycle. Usually a reservoir is involved

/.active transport - against concentration gradient, requires energy expenditure

/.adaptive immunity: specificity - specific

/.Alpha Proteobacteria - Rhizobium and intracellular pathogens (Rickettsia)

/.antibiotic therapy and intestine - disrupts the normal flora and may lead to disease

/.antibody - Y-shaped structure made up of four polypeptides, 2 heavy chains + 2 light
chains.

/.antibody regions - ~constant region and variable region
~tail=Fc region
~arms=Fab regions

/.antigen - any molecule that when introduced in the body will elicit an immune response
(IR) in the form of Antibody production.

/.antiport - coupled transport--the actively transported molecule moves in the direction
opposite to the driving ion

/.arbuscle - Fungi penetrate plant cells forming an arbuscle within a root cell
(endomycorrhizae)

/.Ascomycota - morels and truffles

,/.Assimilation - Process by which organisms acquire an element to build into cells from
an inorganic source:: inorganic-->organic

/.atmospheric N2 --> NH3 (reduced N) - N2 fixation

/.ATP - energy storage molecule in the cell

/.autotroph - inorganic carbon source (CO2)

/.B cells bind to what antigens? - extracellular antigens circulating in blood

/.B cells: function - Differentiate into plasma cells that produce antibodies specific to the
antigen, and memory cells that retains memory of the antigen for a faster response on
second encounter

/.B cells: Type of adaptive immunity involved - Humoral

/.bacteria and methanogens are ________ in the termite gut. - syntrophic (dependent
on each other for the completion of their metabolism)

/.bacteroid - Rhizobia enter plant cells and differentiate into bacteroids (with no cell wall)

/.Basidiomycota - mushrooms

/.benefits of commensals - 1. Make vitamins and digest food (B. thetaiotamicron)
2. Prevent colonization by pathogens (compete with them for food and produce
antibacterial agents that kill them)

/.Beta Proteobacteria - lithotrophs (NH3 oxidizers) Nitrosomonas

/.biosynthetic processes - CO2 fixation
N2 fixation

/.Bordetella pertussis - Whooping cough (toxin destroys lung cilia)

/.Borrelia burgdorferi - Lyme disease (Bull's eye rash)
Vector is tick

/.Campylobacter jejuni - Gastroenteritis

/.Candida albicans causes... - yeast infections

/.catabolism - breakdown of complex food molecules to smaller ones to make ATP

/.cell envelope - everything outside the plasma membrane; gram negatives have outer
membrane, positives do not

, /.cell membrane - keeps things out, semipermeable

/.cell wall - covers the cell membrane

/.cell-mediated immunity - T-cells

/.cell-mediated immunity: Antigen recognized - Antigens are from intracellular
pathogens like viruses and intracellular bacteria that did not enter the cell by
phagocytosis

/.cell-mediated immunity: Host cell involved - Any nucleated cell (including also APC)

/.cell-mediated immunity: Lymphocytes involved and purpose - Cytotoxic T cells destroy
the pathogen.

/.cell-mediated immunity: Mechanism - Cytotoxic T cells recognize the antigen on
surface of infected host cells.

/.cell-mediated immunity: what happens after recognition? - Cytotoxic T cell recognizes
an Ag on MHCI on any nucleated cell surface that was infected with a virus or an
intracellular bacteria

/.cells in adaptive immunity - T-cells, B-cells

/.cells in innate immunity - antigen-presenting cells (macrophages)

/.cells walls are made of... - peptidoglycan (amino acids, NAG, NAM)

/.Cellulolytic bacteria - break down cellulose in cow rumen; will also break down glucose
to pyruvate. H2 accumulates as a result

/.characteristic of stomach that limits microbiota - Low pH, few microbes survive

/.chemical barriers to infection (3) - Acidic pH of stomach,
Lysozymes in tears,
Defensins

/.chemotroph - chemical energy source

/.Chlamydia trachomatis - Chlamydia (Intracellular pathogen)

/.Chloroplasts evolved from - cyanobacteria (genes still encoded on chloroplasts are
photosynthesis genes)

/.Cholera toxin: type of toxin - exotoxin that Disrupts 2º messenger pwy

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