NR 565 - advanced pharmacology midterm - Exam Questions And Correct Answers
3 views 0 purchase
Course
NR565 advanced pharmacology
Institution
NR565 Advanced Pharmacology
NR 565 - advanced pharmacology midterm -
Exam Questions And Correct Answers
During what trimester is a pregnant woman most at risk for adverse drug reactions with potential
long term consequences? - answer1st trimester (fetus most at risk d/t rapid growth)
What is BEERS criteria? - answerRecomm...
NR 565 - advanced pharmacology midterm -
Exam Questions And Correct Answers
During what trimester is a pregnant woman most at risk for adverse drug reactions with potential
long term consequences? - answer✔✔1st trimester (fetus most at risk d/t rapid growth)
What is BEERS criteria? - answer✔✔Recommendations of medications inappropriate for elderly
(65 and older), prescriber ultimately decides
What is the CYP450 (cytochrome P450) - answer✔✔liver enzyme system where medications are
metabolized, can either be inducers or inhibitors and create drug-drug interactions
CYP450 inducers - answer✔✔Speed up metabolism of drugs (drug is cleared faster), drug has
lesser effect (decrease blood levels of drug), elevate CYP450 enzymes
CYP450 inducer drug names - answer✔✔Barbituates, St John wort, Carbamazepine, rifampin,
alcohol, phenytoin, griseofulvin, phenobarbital, sulfonylureas
CYP450 inhibitors - answer✔✔inhibit metabolism, increase blood levels of medications
CYP450 pneumonic - answer✔✔"VISA credit card debt INHIBITS spending on designers like
CK to look GQ"
CYP450 inhibitors drug names - answer✔✔Valproate, isoniazid, sulfonamides, amiodarone,
chloramphenicol, ketoconazole, grapefruit juice, quinidine
Physiological changes during pregnancy that impact pharmacodynamics and pharmacokinetic
properties of drugs? - answer✔✔increase glomerular filtration rate leads to increase durg
excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption
Examples of medications that can be teratogenic - answer✔✔Antiepileptic drugs, antimicrobials
such as tetracyclines and fluoroquinolones, vitamin A in large doses, some anticoagulants, and
hormonal medications such as diethylstilbestrol (DES).
How is absorption of intramuscular medications different in neonates? - answer✔✔slow and
erratic due to low blood flow in muscles first few days of life
Why is absorption of medication in the stomach increased in infancy? - answer✔✔delayed
gastric emptying
Some medications that should be avoided in the pediatric patient? - answer✔✔glucocorticoids,
discoloration of developing teeth with tetracyclines, and kernicterus with sulfonamides,
levofloxacin (antibiotics)
aspirin (Severe intoxication from acute overdose)
what should be included in medication administration patient education? - answer✔✔dosage size
and timing
route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
What are some things that put the elderly patient at higher risk for adverse drug reactions? -
answer✔✔reduced renal function
polypharmacy (the use of five or more medications daily)
greater severity of illness
presence of comorbidities
use of drugs that have a low therapeutic index (e.g., digoxin)
increased individual variation secondary to altered pharmacokinetics
inadequate supervision of long-term therapy
poor patient adherence
How can healthcare providers decrease likelihood of an elderly patient experiencing an adverse
drug reaction? - answer✔✔obtaining a thorough drug history that includes over-the-counter
medications
considering pharmacokinetic and pharmacodynamics changes due to age
monitoring the patient's clinical response and plasma drug levels
using the simplest regimen possible
monitoring for drug-drug interactions and iatrogenic illness
periodically reviewing the need for continued drug therapy
encouraging the patient to dispose of old medications
taking steps to promote adherence and to avoid drugs on the Beers list
How can we promote medication adherence with elderly patients? - answer✔✔simplifying drug
regimens
providing clear and concise verbal and written instructions
using an appropriate dosage form
clearly labeling and dispensing easy-to-open containers
developing daily reminders
monitoring frequently
affordability of drugs
support systems
Why do nitrates need to be taken no later than 4 PM? - answer✔✔Need nitrate free interval so
tolerance doesn't develop
Nine factors that impact outcome of medication? - answer✔✔Gender and race
Genetics and pharmacogenomics
Variability in absorption
placebo effect
Tolerance
patho
age
bodyweight
Do you need informed consent for genetic testing? - answer✔✔yes
What is the purpose of the Genetic Information Non-Discriminatory Act? - answer✔✔Protects
patients from discrimination by employers and insurance providers based on genetic information
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Thebright. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $12.49. You're not tied to anything after your purchase.
