NUR 426 Exam 2 Sirs & Mods Questions and Correct Answers
5 views 0 purchase
Course
NUR 426
Institution
NUR 426
*Response to something- remote response- the body is overly dramatic- Generalized inflammation- at a cellular level- you cannot see it- cellular damage from inflammation-
-infection (sepsis) -ischemia -infarction -injury Causes of SIRS
*sepsis -microbial invasion (bacteria, viruses, fungi, parasi...
NUR 426 Exam 2 Sirs & Mods Questions
and Correct Answers
*Response to something- remote response- the body is overly dramatic- Generalized
inflammation- at a cellular level- you cannot see it- cellular damage from inflammation-
-infection (sepsis)
-ischemia
-infarction
-injury ✅Causes of SIRS
*MECHANICAL TISSUE TRAUMA
-burns (3RD DEGREE; MUCH OF THE BODY)
-crush injuries
-surgical procedures ✅INJURY causing SIRS
•Neutrophils entrapment- first responders in the immune system response- release too
many of them- so not helpful anymore and get in the way and too crowded
•Endothelium damage- fluid seeps out
-release of mediators
, -hypermetabolism
-Activation of coagulation cascade
*hypotension, decreased perfusion, microemboli, and redistributed or shunted blood
flow eventually comprimise organ perfusion ✅Pathophysiology of MODS
•Dilated- and have damage that allows the fluid to seep out causing edema in the
tissues
•Neutrophils- traffic and crowding ✅SIRS PATHO: Capillary Permeability
*2 out of 4 criteria*
-Temp > 38 ºC (100.5º F) or < 36 ºC (96.8º F)
-Respiratory rate> 20 or PaCO2 <32 (why is CO2 low? Blowing off so much)
-Heart rate >90
-White blood cells >12,000 or <4,000 or >10% bands (immature WBC) ✅SIRS Criteria
Sepsis ✅SIRS + confirmed Infection (culture)=
Septic Shock ✅Sepsis + LOW B/P despite fluids
*failure of two or more organ systems
-MODS mortality rates are 70% to 80% when three or more organ systems fail
-Results from SIRS
-Associated with widespread endothelial and cell injury
-Homeostasis cannot be maintained without intervention
-The respiratory system is often the first system to show signs of dysfunction in SIRS
and MODS, often culminating in acute respiratory distress syndrome (ARDS).
-Cardiovascular changes, neurologic dysfunction, acute kidney injury, DIC, GI
dysfunction, and liver dysfunction are common
*•When it gets to 3 or more organ failures, you're SOL (crap out of luck)
•They have to have LOTSSSS of interventions ✅Multiple organ dysfunction syndrome
(MODS)
-Direct damage to the endothelium --> Increase in vascular permeability --> Mediators
and protein leak out of endothelium into interstitial space --> Hypotension and
decreased perfusion ✅Patho of SIRS: RELEASE OF MEDIATORS
Formation of microemboli ✅Patho of MODS: Activation of coagulation cascade
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller twishfrancis. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $8.99. You're not tied to anything after your purchase.
