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Exam (elaborations)

USMLE STEP 1 RAPID REVIEW

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USMLE STEP 1 RAPID REVIEW

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  • August 29, 2024
  • 12
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • USMLE
  • USMLE
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GEEKA
USMLE STEP 1 RAPID REVIEW
Abdominal pain, ascites, hepatomegaly, (also high D dimer, CHF without JVD) -
Answers -Budd-Chiari syndrome

Achilles tendon xanthoma - Answers -Familial hypercholesterolemia

Adrenal hemorrhage, hypotension, DIC - Answers -Waterhouse-Friderichsen syndrome
(meningococcemia)

Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints - Answers -
Marfan's (fibrillin defect)

Athlete with polycythemia - Answers -Erythropoietin injection

Back pain, fever, night sweats, weight loss - Answers -Pott's (TB to the vertebrae)

Bilateral hilar adenopathy, uveitis - Answers -Sarcoid

Blue sclera - Answers -Osteogenesis imperfecta

Bluish line on gingiva - Answers -Burton's line - lead poisoning

Bone pain, bone enlargement, arthritis, (also increased hat size, fracture, increased alk
phos) - Answers -Paget's

Bounding pulses, diastolic hear murmur, head bobbing - Answers -Aortic regurg

Café-au-lait spots, Lisch nodules - Answers -NF (1 = optic glimoas and pheo, 2 =
acoustic Schwannomas)

Café-au-lait spots, polyostotic fibrous dysplasia, precocious puberty - Answers -
McCune-Albright syndome (G protein problem)

Calf pseudohypertrophy - Answers -Duchenne's muscular dystrophy

Cherry-red spot on macula - Answers -Tay-Sachs, Niemann-Pick, central retinal artery
occlusion

Chest pain, pericardial effusion/friction rub, persistent fever following MI - Answers -
Dressler's (autoimmune post-MI)

Child uses arms to stand up from squat - Answers -Gower's sign (Duchenne's)

Child with fever develops red rash on face that spreads to body - Answers -Slapped
cheek - B19

, Chorea, dementia, caudate degeneration - Answers -Huntington's

Chronic exercise intolerance with myalgia, fatigue, painful cramps - Answers -McArdle's
(muscle phosphorylase deficiency)

Cold intolerance - Answers -Hypothyroidism

Hereditary nephritis, sensorineural hearing loss, cataracts - Answers -Alport's syndrome
(type IV collagen)

Hypercoagulability leading to thrombophlebitis - Answers -Trousseau's sign
(adenocarcinoma of pancreas or lung)

Hyperphagia, hypersexuality, hyperorality, hyperdocility - Answers -Kluver-Bucy
syndrome (bilateral amygdala)

HTN, hypoK, metabolic alkalosis - Answers -Conn's (1* hyperaldosterone)

Hypoxemia, polycythemia, hypercapnia - Answers -Blue bloater (chronic bronchitis)

Indurated, ulcerated genital lesion - Answers -Nonpainful = syphillis. Painful with
exudate = chancroid

Infant with failure to thrive, hepatosplenomegaly, neurodegeneration - Answers -
Niemann-Pick disease (genetic sphingomyelinase deficiency)

Infant with hypoglycemia, failure to thrive, and hepatomegaly - Answers -Cori's disease
(debranching enzyme deficiency, no glycogenolysis) or Von Gierke's

Infant with microcephaly, rocker-bottom feet, clenched hands, and structural heart
defect - Answers -Edward's syndrome (Trisomy 18)

Jaundice, RUQ pain, fever - Answers -Charcot's triad (ascending cholangitis)

Keratin pearls - Answers -Squamous cell carcinoma

Large rash with bull's eye appearance - Answers -Erythema chronicum migrans from
Ixodes tick bite (Lyme)

Lucid interval after TBI - Answers -Epidural hematoma (middle meningeal artery)

Male child, recurrent infections, no mature B cells - Answers -Bruton's disease (X-linked
agammaglobulinemia)

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