C785 final biochemistry Exam Questions and Correct Verified Answers
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Course
Biochemistry
Institution
Biochemistry
Which force is most impacted by this change in pH? - ANSWER Ionic bonds
An active elderly patient is becoming frequently disoriented, having trouble recalling her
daily routine, and becoming aggravated easily. She forgets words and places and has
difficulty recognizing her children.
Which bioch...
C785 final biochemistry Exam
Questions and Correct Verified Answers
Which force is most impacted by this change in pH? - ANSWER Ionic bonds
An active elderly patient is becoming frequently disoriented, having trouble recalling her
daily routine, and becoming aggravated easily. She forgets words and places and has
difficulty recognizing her children.
Which biochemical event is responsible for this patient's behavior? - ANSWER
Protein aggregation
In which situation would altering a protein structure lead to a disease state? - ANSWER
A mutation in aconitase blocks an essential step in aerobic metabolism
How can an alteration in protein structure lead to a disease state? - ANSWER A
mutation replaces an isoleucine with an aspartic acid in a transcription factor
protein, which blocks the normal folding of the protein and its function in the
expression of certain genes.
Which structural level shows the greatest difference when replacing denatured
proteins with a denatured single subunit protein? - ANSWER Tertiary
Frying an egg changes the egg white from a clear liquid to an opaque solid.
Which molecular change in the albumin protein causes this change in appearance? -
ANSWER Hydrophobic interactions form between denatured egg white proteins.
, What is the driving mechanism of plaque formation in prion diseases? - ANSWER
Propagation of misfolding from one protein to another
Which feature of a protein made of a single polypeptide chain is most
directly responsible for its function? - ANSWER Three-dimensional structure
How does the Bohr effect describe the relationship between carbon dioxide levels,
blood pH and the amount of oxygen bound to hemoglobin? - ANSWER An increase in
carbon dioxide production leads to a decrease in blood pH, causing hemoglobin to
release oxygen more readily.
Which statement describes the binding of oxygen gas to a heme group? - ANSWER
The binding of oxygen gas to heme changes the structure of the heme group.
Which characteristic of myoglobin makes it an effective oxygen storage molecule? -
ANSWER It has a high affinity for oxygen.
At low O 2 concentrations, how does myoglobin's affinity for O 2 relate to
hemoglobin's affinity for O 2? - ANSWER Myoglobin has a much greater affinity for O
2 than hemoglobin does.
Which pair of binding curves accurately compares how hemoglobin and myoglobin
become saturated with oxygen as a function of the partial pressure of oxygen? -
ANSWER option 2
How does pH level promote the deoxygenated conformation of hemoglobin? - ANSWER
When pH lowers, O 2 binds with excess HCO 3 - in the blood, which blocks its ability to
bind to the heme group and pull it into the dome conformation.
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