EPPP- Neurocognitive Disorders (PrepJet)
Practice Questions and Answers
What criteria is required to diagnose major neurocognitive disorder
probable Alzheimers? - Answer✔️✔️-evidence of a causative genetic
mutation from genetic testing or family history and/or evidence of a
decline in memory and learning and at least one other cognitive domain, a
steadily progressive and gradual decline in cognition, and no evidence of a
mixed etiology
What is the age of of early onset Alzheimer's? - Answer✔️✔️-the early-onset
subtype applying to individuals whose symptoms had an onset at 65 year
of age or younger.
What does the term pseudodementia refer to? - Answer✔️✔️-depression that
has prominent cognitive symptoms.
How do people with pseudodementia respond to treatment? - Answer✔️✔️-
people with pseudodementia usually respond well to treatment, and they
have an abrupt onset of symptoms, exaggerate their cognitive problems,
have moderate memory loss and symptoms of melancholia and anxiety,
and often say "I don't know in response" to assessment questions. I
What are genetic risks for Alzheimer's? - Answer✔️✔️-the ApoE4 variant on
chromosome 19.
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What are neurotransmitter abnormalities in Alzheimer's? - Answer✔️✔️-
reduced acetylcholine (ACh) and excessive glutamate, which are both
known to be involved in learning and memory.
What are the areas in the brain first affected by Alzheimer's? - Answer✔️✔️-
here's also evidence that the locus coeruleus (an area in the brain stem) is
the first area of the brain to be affected by Alzheimer's disease and shows
abnormalities before the appearance of symptoms. Then, the temporal lobe.
Describe the early stages of Alzheimer's - Answer✔️✔️-The early stage lasts
for about two to four years and involves anterograde amnesia, personality
changes and mood disturbances, impaired attention and judgment, and
anomia (difficulty recalling names of familiar people and objects).
Describe the middle stages of Alzheimer's - Answer✔️✔️-he middle stage
which lasts for two to 10 years. Its symptoms include increasing
anterograde and retrograde amnesia, disorientation to time and place,
anxiety or depression, delusions, wandering and pacing, compulsive and
repetitive behaviors, impaired speech, disruption in sleep patterns, and
problems with normal daily activities.
Describe the final stages of Alzheimer's - Answer✔️✔️-the late stage usually
lasts for one to three years and involves severely deteriorated intellectual
functioning, severe disorientation, apathy, severely impaired speech,
agitation and aggression, urinary and fecal incontinence, loss of basic
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