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Genetics Research in Human Populations

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Genetics Research in Human Populations Definitions and Key Concepts 1. Genetic Determinism - Best Definition: - ️ Genes are primarily responsible for human traits, including health, behavior, and disease. Usage of Biospecimens 2. Biospecimens and Research Focus - Investigator A's Researc...

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  • August 29, 2024
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  • 2024/2025
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  • Genetics Research in Human Populations
  • Genetics Research in Human Populations
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Genetics Research in Human Populations
Definitions and Key Concepts



1. Genetic Determinism

- Best Definition:

- ✔️ Genes are primarily responsible for human traits, including health, behavior, and disease.



Usage of Biospecimens



2. Biospecimens and Research Focus

- Investigator A's Research:

- Conducts research on emphysema with human subjects' biospecimens.

- Consent indicates a focus exclusively on emphysema.

- Investigator B's Research:

- Wishes to use those biospecimens for lung cancer research.

- Can Investigator B use the specimens without re-consent if they are de-identified?

- ✔️ Yes, if the biospecimens are de-identified, then the research is no longer considered human
subjects research.



Re-Contacting Participants



3. Conditions for Re-Contacting Individuals:

- When is it appropriate?

- ✔️ Original signed consent documents include provisions for re-contacting subjects.



NIH Genetic Research Guidelines (as of January 2015)



4. Informed Consent in NIH-Funded Genetic Research:

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